No ‘ideal’ tissue for gene expression studies of autism
Researchers should investigate a broad spectrum of human- and animal-derived tissues to fully capture the complexity of autism, say Michael Talkowski and James Gusella.
Researchers should investigate a broad spectrum of human- and animal-derived tissues to fully capture the complexity of autism, say Michael Talkowski and James Gusella.
Mutations in a gene associated with DNA packaging may lead to autism and intellectual disability, suggests a study published 16 February in Nature Genetics.
Researchers have established a set of commercially available cell lines that can help gauge the quality of tests for Rett syndrome, they reported in the March issue of the Journal of Molecular Diagnostics.
Watch the complete replay of Joseph Gleeson explaining how DNA sequencing can help find treatments, including dietary supplements, for rare types of autism.
A teenager with fragile X syndrome carries a rare mutation that changes a single amino acid in the FMRP protein, researchers reported 22 January in the European Journal of Human Genetics.
It takes more mutations to trigger autism in women than in men, which may explain why men are four times more likely to have the disorder, according to a study published 26 February in the American Journal of Human Genetics.
An artificial-intelligence algorithm designed to analyze behavior has learned to recognize six genetic disorders associated with autism, according to a report published 11 February in Molecular Autism. The algorithm could be used to hone the search for autism’s genetic underpinnings.
Autism researchers have high hopes for a new project called the First 1,000 Days of Life, which aims to follow 5,000 women and their babies from pregnancy through two years after birth.
A new paper accomplishes a rare feat, linking human genetics with physiology, behavior and a therapeutic in a compelling mouse model of autism, says Alan Packer.
Spontaneous and rare mutations, particularly in genes related to networks that regulate neuronal connections, contribute a small but significant proportion of the risk for schizophrenia, report two large studies published online 22 January in Nature.