Mutations in both copies of a gene called ACTL6B lead to autism, epilepsy and intellectual disability.
Some cells in brain organoids — 3D clusters of cultured brain cells — fail to develop fully.
The mutation that causes Angelman syndrome makes neurons hyperexcitable, which may explain the frequent seizures that most people with the syndrome have.
Researchers have analyzed thousands of brain organoids derived from six autistic people, gaining the potential to rapidly screen drugs.
Alysson Muotri aims to build a ‘thinking’ brain as a model for autism — even if his colleagues consider that work controversial.
A new method enables scientists to grow organoids that reliably reproduce the diversity of cells at the brain’s surface.
A cache of about 100 brain organoids grown from human cells is expected to launch into orbit this month.
A novel cell culture device enables researchers to grow bundles of nerve fibers from stem cells, mimicking the tissue that connects distant parts of the brain.
Lilia Iakoucheva spends her days running outdoors and solving the molecular complexities of autism, sometimes at the same time.