Tag: GWAS

May 2015
News

New approach powers up search for autism genes

by  /  19 May 2015

A statistical trick can help researchers home in on subtle genetic blips that contribute to autism, according to unpublished results presented Saturday at the 2015 International Meeting for Autism Research in Salt Lake City, Utah.

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March 2015
News

Landscape of chemical tags paves way for autism studies

by  /  2 March 2015

In a feat that unites findings from 2,800 experiments in more than 100 types of cells, researchers have mapped the human epigenome — the many layers of code that turn genes on or off.

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February 2015
Multimedia / Webinars

Kathryn Roeder reviews statistical tools for autism

18 February 2015

Watch the complete replay of Kathryn Roeder’s webinar discussing how powerful statistical tools can yield insight into the genetic risk for autism.

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October 2014
News / Toolbox

New resource catalogs impact of DNA variants on brain

by  /  22 October 2014

A new online database called Braineac details how variations in DNA sequence shape gene expression in the human brain.

0 Comments
News

Web of genes may hold clues for autism treatments

by  /  20 October 2014

Many of the genes that have emerged as the strongest autism candidates have turned out to regulate the expression of hundreds, if not thousands, of other genes. Within these networks, scientists are homing in on pathways that underlie autism.

6 Comments
August 2014
Opinion / Cross Talk

Should autism research focus on common or rare risk factors?

by  /  20 August 2014

New estimates on the role of common mutations in autism raise questions about how to quantify and parse genetic risk. Three experts say both common and rare variants are worth pursuing.
 

5 Comments
July 2014
Opinion / Viewpoint

Schizophrenia milestone holds lessons for autism

by  /  21 July 2014

A long-awaited report, published today in Nature, confirms that with access to tens of thousands of genomes, researchers can identify common genetic risk factors for a complex neuropsychiatric disorder.

1 Comment
News

Common mutations account for half of autism risk

by  /  21 July 2014

Common genetic variants that have minor effects may contribute about half the risk of developing autism, according to a study published Sunday in Nature Genetics. Identifying these variants would require tens of thousands of samples.

13 Comments
May 2014
News / Toolbox

Massive atlas documents genome’s regulatory regions

by  /  7 May 2014

Researchers have sequenced hundreds of human and mouse genomes to generate an atlas of more than 200,000 regions that regulate gene expression, they reported 27 March in Nature.

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February 2014
News

Genetics: Chinese population study identifies new autism gene

by  /  11 February 2014

Mutations in TRIM33, a protein that is part of the cell’s cleanup crew, may up the risk for autism, according to a study published 5 November in Molecular Psychiatry.

3 Comments