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Spectrum: Autism Research News

Tag: GWAS

October 2014

Web of genes may hold clues for autism treatments

by  /  20 October 2014

Many of the genes that have emerged as the strongest autism candidates have turned out to regulate the expression of hundreds, if not thousands, of other genes. Within these networks, scientists are homing in on pathways that underlie autism.

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August 2014

Should autism research focus on common or rare risk factors?

by  /  20 August 2014

New estimates on the role of common mutations in autism raise questions about how to quantify and parse genetic risk. Three experts say both common and rare variants are worth pursuing.
 

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July 2014

Common mutations account for half of autism risk

by  /  21 July 2014

Common genetic variants that have minor effects may contribute about half the risk of developing autism, according to a study published Sunday in Nature Genetics. Identifying these variants would require tens of thousands of samples.

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Schizophrenia milestone holds lessons for autism

by  /  21 July 2014

A long-awaited report, published today in Nature, confirms that with access to tens of thousands of genomes, researchers can identify common genetic risk factors for a complex neuropsychiatric disorder.

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May 2014

Massive atlas documents genome’s regulatory regions

by  /  7 May 2014

Researchers have sequenced hundreds of human and mouse genomes to generate an atlas of more than 200,000 regions that regulate gene expression, they reported 27 March in Nature.

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February 2014

Genetics: Chinese population study identifies new autism gene

by  /  11 February 2014

Mutations in TRIM33, a protein that is part of the cell’s cleanup crew, may up the risk for autism, according to a study published 5 November in Molecular Psychiatry.

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October 2013

Genetics: Common variants key in psychiatric inheritance

by  /  1 October 2013

More of the common variants implicated in schizophrenia are also linked to bipolar disorder than to autism, according to a study published 28 August in Nature Genetics.

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July 2013

Fuzzy network

by  /  5 July 2013

A new network analysis of autism genes, published 11 June in Translational Psychiatry, highlights both the pitfalls and the promise of the approach, says Alan Packer.
 

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June 2013

Rare, common variants together boost gene analysis

by  /  5 June 2013

A new statistical method for linking genes to a disorder analyzes both rare and common variants of a gene at the same time, according to a study published 14 May in the American Journal of Human Genetics. This makes it possible to confirm associations that other techniques might overlook.

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May 2013

Small pieces of RNA may pave path to autism

by  /  21 May 2013

The discovery of microRNAs that regulate gene expression has changed our view of cellular biochemistry. It may also change our perception of neuropsychiatric disorders such as autism, says Peng Jin.

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