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Spectrum: Autism Research News

Tag: astrocytes

February 2021
Oligodendrocyte gene grouping showing network of blue lines connecting the gene names on reddish bubbles.

Differing gene functions across species may pose problems for autism models

by  /  22 February 2021

Misaligned gene expression maps suggest that some autism-linked genes play distinct roles in mouse and human brains.

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May 2020

Extra proteins alter microglia and behavior in mice

by  /  29 May 2020

The overproduction of proteins in brain cells called microglia causes social impairments, cognitive deficits and repetitive behavior in male mice, a new study has found.

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brain shown in four distinct, colorful layers

New mapping technique reveals unexpected brain cell diversity

by  /  13 May 2020

Star-shaped cells called astrocytes may play a greater role in brain development than previously thought.

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May 2019
Individual cells from the brains of autistic people show distinct gene-expression patterns, and are shown in different colors.

Analysis of single cells implicates set of neurons in autism

by  /  22 May 2019

A set of neurons involved in complex cognitive functions may play a central role in autism.

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September 2018

Autism’s sex bias may originate in brain’s immune cells

by  /  5 September 2018

The brain’s immune cells, called microglia, function differently in male and female rodents. In people, a similar phenomenon may make male brains more vulnerable to autism.

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Charting one cell at a time, scientists reveal brain’s vast diversity

by  /  3 September 2018

How many cell types does the brain contain? Two new mouse studies bring scientists closer to the answer.

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May 2018
Blood vessels seen at magnification.

Human ‘mini-brains’ make themselves at home in mice

by  /  23 May 2018

Spheres of brain cells derived from people and implanted into mouse brains recruit blood vessels and integrate with mouse neurons.

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February 2018
etworks of genes derived from certain 'modules' (neuron, top right, and astrocyte, bottom left) are altered in autism, schizophrenia and bipolar disorder.

Autism shares brain signature with schizophrenia, bipolar disorder

by  /  8 February 2018

Gene expression patterns in the brains of people with autism are similar to those of people who have schizophrenia or bipolar disorder.

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September 2017
After months in culture, stem cells (left) develop into mature brain cells, including star-shaped astrocytes (right).

Lab-grown spheres yield star-shaped brain cells

by  /  22 September 2017

A new technique allows researchers to generate brain cells called astrocytes and maintain them in culture as they mature.

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January 2017

Diverse causes of autism converge on common gene signature

by  /  23 January 2017

The brains of people with autism show a distinct molecular signature that reflects alterations in how genes are pieced together and expressed.

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