Differing gene functions across species may pose problems for autism models
Misaligned gene expression maps suggest that some autism-linked genes play distinct roles in mouse and human brains.
Misaligned gene expression maps suggest that some autism-linked genes play distinct roles in mouse and human brains.
The overproduction of proteins in brain cells called microglia causes social impairments, cognitive deficits and repetitive behavior in male mice, a new study has found.
Star-shaped cells called astrocytes may play a greater role in brain development than previously thought.
A set of neurons involved in complex cognitive functions may play a central role in autism.
The brain’s immune cells, called microglia, function differently in male and female rodents. In people, a similar phenomenon may make male brains more vulnerable to autism.
How many cell types does the brain contain? Two new mouse studies bring scientists closer to the answer.
Spheres of brain cells derived from people and implanted into mouse brains recruit blood vessels and integrate with mouse neurons.
Gene expression patterns in the brains of people with autism are similar to those of people who have schizophrenia or bipolar disorder.
A new technique allows researchers to generate brain cells called astrocytes and maintain them in culture as they mature.
The brains of people with autism show a distinct molecular signature that reflects alterations in how genes are pieced together and expressed.