Long cast in supporting roles in the brain, astrocytes are now emerging as primary players in certain characteristics of autism and related conditions.
Spectrum: Autism Research News
Many genes linked to autism are switched on in the brain’s glia, cells that help neurons develop and synapses form.
A MECP2 gene therapy for Rett syndrome eases repetitive behaviors, anxiety and hyperactivity in a mouse model of Pitt-Hopkins syndrome.
Misaligned gene expression maps suggest that some autism-linked genes play distinct roles in mouse and human brains.
The overproduction of proteins in brain cells called microglia causes social impairments, cognitive deficits and repetitive behavior in male mice, a new study has found.
Star-shaped cells called astrocytes may play a greater role in brain development than previously thought.
A set of neurons involved in complex cognitive functions may play a central role in autism.
The brain’s immune cells, called microglia, function differently in male and female rodents. In people, a similar phenomenon may make male brains more vulnerable to autism.
How many cell types does the brain contain? Two new mouse studies bring scientists closer to the answer.
Spheres of brain cells derived from people and implanted into mouse brains recruit blood vessels and integrate with mouse neurons.