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Study hints at microbiome differences in children with autism

by  /  14 January 2021

Children with autism may have a subtly different set of bacteria in their gut than their non-autistic siblings do.

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Illustration of firing neurons.

Autism protein may shape neuronal firing patterns

by  /  14 January 2021
Cells with excess UBE3A, an autism-linked protein, have atypical firing properties that can be corrected by limiting the protein's levels, according to new research.
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Lost sleep sparks lasting social problems in SHANK3 mice

by  /  14 January 2021
Sleep disruption early in life has long-lasting consequences for mice missing a copy of the autism-linked gene SHANK3.
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New gene therapy methods deliver promise

by  /  14 January 2021
Two unpublished studies detail improved techniques for delivering gene therapies to the brain.

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Molecular model of histone protein which wraps up DNA strands.
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New condition hints at structural protein’s role in autism

by  /  22 January 2021

Mutations in genes that encode a histone, which gives structure to chromosomes, can lead to developmental delay and congenital anomalies.

DNMT3A protein attaches a methyl group tag onto the DNA base cytosine.
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Autism-related conditions converge on same loss of DNA tags

by  /  20 January 2021

Mutations in the autism-linked gene DNMT3A lead to the behaviors and gene-expression changes seen in different neurodevelopmental conditions.

human brain lights up with connections within a network
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Community newsletter: All about SfN Global Connectome

by  /  19 January 2021

We dove into what people on social media thought about the SfN Global Connectome 2021 conference — and its virtual format.

Brain pattern with people gathering
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Highlights, missed opportunities: SfN by the tweets

by  /  15 January 2021

Participants video chatted and tweeted their way through the Society for Neuroscience’s three-day virtual conference this week.

girl about to catch a ball
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Autistic children may have trouble predicting movements

by  /  15 January 2021

Autistic children may have a harder time catching a ball than non-autistic children do, possibly because they are less able to predict its trajectory.

Mouse with her pup
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Malfunctioning neurons mute sound processing in mouse model of Rett syndrome

by  /  14 January 2021

Female mice missing a copy of the autism-linked gene MECP2 in a specific set of inhibitory neurons have a hard time heeding pups’ calls and herding litters.

Mouse on gray background looks at something out of frame.
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Inability to attend to cues may cause sensory challenges in fragile X mice

by  /  14 January 2021

Sensory problems in people with fragile X syndrome may stem from hyperactive neurons, a mouse model study suggests.

Scans of mouse brain slices showing differences in oxytocin levels
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Oxytocin alters brain activity to boost sociability in mice missing autism gene

by  /  13 January 2021

Infusions of the hormone oxytocin may make mice that model autism more social by normalizing their brain activity patterns.

Boy sleeping in low light
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Brain-wave patterns flag sleep differences in dup15q syndrome

by  /  13 January 2021

Children with dup15q syndrome may have telltale patterns of brain activity during sleep and get less non-REM sleep than neurotypical children do.

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Two top autism genes may have a mechanism in common

by  /  13 January 2021

Mutations in two genes linked to autism and intellectual disability boost the immune response and cause synapse dysfunction.

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