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Differing gene functions across species may pose problems for autism models

by  /  22 February 2021

Misaligned gene expression maps suggest that some autism-linked genes play distinct roles in mouse and human brains.

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Mutations in frogs point to autism genes’ shared role in neurogenesis

by  /  10 February 2021
Mutations in any of 10 autism-linked genes in frogs lead to the same overabundance of brain cells that develop into neurons; the sex hormone estrogen lowers this excess.
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Transmission Electron micrograph shows mitochondria colored an aqua blue.

Changes to mitochondrial DNA spur autism-like traits in mice

by  /  17 February 2021
Mice with a mutation in their mitochondrial DNA show altered brain activity, repetitive behaviors and reduced sociability, according to a new study.
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Singing zebra finches

Autism gene interference silences song memory in birds

by  /  19 February 2021
Muffling expression of an autism-linked gene in a key song-related area of the brain renders young zebra finches unable to learn songs from older birds.

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Proteins linked to top autism gene might aid early diagnosis

by  /  26 February 2021

Blood levels of PTEN protein and associated molecules could eventually help diagnose autism and other neurological conditions — and predict their outcomes.

Female teen in an institutional setting, blue light by widows, blinds drawn.
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Emotional challenges predict hospital stays in autistic children

by  /  24 February 2021

Autistic children who have difficulty managing their emotions are also likely to take medication and need assistance from emergency responders.

Speech bubble formed by a network of communication
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Community newsletter: Anorexia services for autistic women, camouflaging and mental health, INSAR goes virtual again

by  /  21 February 2021

In this week’s community newsletter, we discuss a paper that looked at what autistic women with eating disorders say about services offered to them.

mouths forming a conversation
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Community newsletter: All about cognitive flexibility

by  /  14 February 2021

In this week’s community newsletter, we discuss a new paper on cognitive and behavioral flexibility and why it’s important during the COVID-19 pandemic.

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Genetic variants in protein target sites may contribute to autism

by  /  12 February 2021

Mutations that disrupt binding sites in RNA molecules may play a role in autism and a variety of psychiatric conditions, according to a new study.

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Advancing early interventions for autism

by  /  9 February 2021

Some therapies use play and other activities to reinforce skills that autistic children often find challenging. Trials show these methods can change a child’s trajectory for the better, but the evidence base remains thin.

Man reaches into cabinet while a woman looks on
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Single neurons may power key ‘theory of mind’ skills

by  /  8 February 2021

A subset of brain cells signal when someone tries to infer another person’s thoughts, according to a new study.

Speech bubble formed by a network of communication
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Community newsletter: Research on camouflaging; a new epigenome

by  /  7 February 2021

In this week’s community newsletter, we talk about a new paper on camouflaging and a thorough human epigenome.

Serotonin proteins
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Sensor helps scientists spy on serotonin activity in mice in real time

by  /  5 February 2021

A glowing protein tracks serotonin levels and location in the brains of living mice and could yield clues to the neurotransmitter’s role in autism.

four figures overlapping in red and blue with multi-colored genetic info
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Common variants link autism, ADHD, Tourette syndrome

by  /  2 February 2021

Genetic variants that contribute to autism may also be involved in attention deficit hyperactivity disorder and Tourette syndrome, according to a new study.

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