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Largest study to date confirms overlap between autism and gender diversity

by  /  14 September 2020

People who do not identify with the sex they were assigned at birth are three to six times as likely to be autistic as cisgender people are.

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Fragile X syndrome traits may stem from leaky mitochondria

by  /  11 September 2020
Plugging a leaky mitochondrial membrane may help fragile X neurons to mature and function more efficiently.
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Colorful chart showing variants in chromosomes.

Scan of genomes for inherited variants lays bare new autism candidate

by  /  10 September 2020
Lowered expression of a gene called DDHD2 may increase a person's likelihood of having autism, according to a new analysis.
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Neurons in a macaque cortex express parvalbumin in red.

Virus-based method manipulates inhibitory neurons in brains

by  /  9 September 2020
A new viral tool can selectively control different types of neurons that dampen brain activity in rodents, monkeys and people.

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Gender and sexuality in autism, explained

by  /  18 September 2020

Gender and sexuality appear to be more varied among autistic people than among neurotypical people. What do scientists know about the connection?

Brain images showing differences in signaling in autistic and normal brains.
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Brain signal imbalance tracks with sex and with camouflaging autism traits

by  /  17 September 2020

Autistic men show a greater imbalance between excitatory and inhibitory signaling in the brain than autistic women do, which could explain sex differences in ‘camouflaging.’

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Cannabis and autism, explained

by  /  7 September 2020

Autistic people and their families are increasingly experimenting with marijuana to try to ease problems such as insomnia, epilepsy and chronic pain — and traits of autism. But there is little evidence for its safety or effectiveness.

Liquid medicine being poured from bottle onto spoon.
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Bumetanide may benefit only a subset of autistic children

by  /  3 September 2020

Contrary to previous results, the blood pressure drug did not uniformly improve autism traits in a new clinical trial.

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Autism prevalence in the United States explained

by  /  3 September 2020

The bulk of the increase in autism prevalence stems from a growing awareness of the condition and changes to the diagnostic criteria.

DNA inside of human form
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Autism genetics, explained

by  /  3 September 2020

The more scientists dig into DNA, the more intricate its contribution to autism seems to be. Here, we unravel the complex genetics of autism.

Two mice side-by-side.
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Drug improves social behaviors, oxytocin signaling in autism mouse model

by  /  31 August 2020

Mice missing the autism gene NLGN3 have altered social behaviors and brain responses to the hormone oxytocin, both of which improve after treatment with a drug that helps regulate protein production.

Two faces interacting socially while data is being recorded, illustration.
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Facial expressions between autistic and typical people may be mismatched

by  /  28 August 2020

Conversations between an autistic and a typical person involve less smiling and more mismatched facial expressions than do interactions between two typical people.

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DNA droplets may be key to Rett syndrome, researchers say

by  /  27 August 2020

Mutations in the MECP2 gene, which are associated with autism and Rett syndrome, interfere with a cell’s ability to form droplets of DNA that silence gene expression.

RNA, transcription
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Antidote to ‘poison’ DNA may treat lethal form of epilepsy

by  /  26 August 2020

An experimental drug silences a DNA segment and seems to prevent seizures and death in a condition related to autism.

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