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Finding a path forward for fragile X drugs

by  /  23 September 2021

The stubborn lack of treatments for fragile X syndrome — a leading cause of inherited intellectual disability and autism — is spurring researchers to revise clinical trial techniques and revisit old drug candidates.

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Uncertainty clouds test of ‘preemptive’ therapy to ease autism traits

by  /  24 September 2021
Experts question data showing that an experimental therapy that parents deliver to babies with early signs of autism can lessen the intensity of the children’s traits and lower their chances of diagnosis at age 3.
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Analysis ups estimate of spontaneous mutations’ role in autism

by  /  27 September 2021
Spontaneous genetic mutations contribute to autism in 30 to 39 percent of all people with the condition, and 52 to 67 percent of autistic children whose siblings do not also have the condition.
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Repetitive behaviors wax and wane among autistic youth

by  /  20 September 2021
Some types of restricted and repetitive behaviors become more prevalent among autistic children and teenagers over time, depending on their age and intellectual ability, whereas others decrease.

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No link between epidurals and autism, two studies confirm

by  /  28 September 2021

Children born to people given an epidural during labor do not have an increased chance of having autism, according to two new studies.

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The search for a link between autism and neurodegenerative conditions

by  /  28 September 2021

Autistic people have a higher-than-average chance of developing a neurodegenerative condition, according to a few studies. Some scientists are searching for proof — work that could also improve care for older autistic adults.

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Community Newsletter: Anti-racism in clinical practice, bilingualism and autism

by  /  26 September 2021

In this week’s Community Newsletter, we look at a call to end anti-Black racism and a commentary on the benefits of and barriers to raising bilingual autistic children.

Illustration of hybrid objects: part light bulb, part lab vial, some in blue and some in red to signify null and replicated results
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Null and Noteworthy: Null rejection, repetitive behaviors, unsuccessful treatments

by  /  23 September 2021

In this edition of Null and Noteworthy, tests of intranasal oxytocin and an Angelman syndrome treatment fail to see results.

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Community Newsletter: Spectrum survey on 2021 conferences, Bayesian precision, paper review feedback

by  /  19 September 2021

In this week’s Community Newsletter, we serve up a survey on conference attendance over the next few months, a paper on the Bayesian brain’s relationship to precision and a tweet about constructive peer reviews.

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Severe infection may raise odds of autism in some children

by  /  17 September 2021

Mock viral infections impair social memory in mice with a mutation tied to autism, and autistic boys are more likely than their non-autistic peers to have had serious infections early in life.

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Spectrum survey: Attending scientific conferences and meetings

by  /  16 September 2021

Help Spectrum report on the pandemic’s effect on conference plans by participating in a brief survey.

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Mutations linked to autism may be detectable in men’s sperm

by  /  16 September 2021

An advanced DNA-sequencing technique has identified gene-damaging mutations, some with ties to autism, in about 1 in 15 men.

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By the Numbers: Machine learning, dementia link, antipsychotics while pregnant

by ,  /  16 September 2021

In this edition of By the Numbers, we discuss machine learning for autism, early-onset dementia, and antipsychotic medicines during pregnancy.

Four brains showing areas affected by the X chomosome in yellow
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X chromosome exerts extra influence on brain development

by  /  15 September 2021

The X chromosome holds stronger-than-expected genetic sway over the structure of several brain regions. The genes that may underlie this oversized influence have ties to autism.

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