Skip to main content

Tag: Rett syndrome

May 2015
News

Study questions promise of bone marrow transplant for Rett

by  /  22 May 2015

Researchers from four labs were unable to reproduce the findings from a high-profile 2012 study in which bone marrow transplants dramatically extended the lives of mice with features of Rett syndrome. Their sobering findings were published yesterday in Nature.

1 Comment
April 2015
News

Rett mutation may lead to runaway inflammation

by  /  30 April 2015

The mutation that causes Rett syndrome may spark uncontrolled inflammation throughout the body and brain, suggests a study published last week. The findings may explain the syndrome’s wide range of symptoms, from seizures to gut problems.

1 Comment
News

New data implicate unusually long genes in Rett syndrome

by  /  13 April 2015

Mutations in MeCP2, which cause Rett syndrome, boost the expression of long genes in the brain. The findings add to mounting evidence linking long genes to developmental disorders.

2 Comments
February 2015
News

Autism gene guides early neuron development

by  /  12 February 2015

The little-studied autism gene ANKRD11 helps to package DNA in the nucleus and plays a critical role in the early growth and positioning of neurons.

2 Comments
December 2014
Opinion

Sequencing may offer smoother sailing in diagnostic odyssey

by  /  16 December 2014

Getting to a diagnosis of autism or another neurodevelopmental disorder is a long and frustrating experience for some families — especially when it comes to finding the underlying genetic cause. DNA sequencing could ease this arduous journey.

3 Comments
November 2014
News

Monkey missing Rett gene prompts primate research debate

by  /  20 November 2014

Scientists have created a transgenic monkey modeling Rett syndrome, they announced yesterday at the 2014 Society for Neuroscience annual meeting in Washington, D.C. This model and others sparked a lively discussion about the relative value of animal models in research.

0 Comments
News

In mouse model of Rett, immune cells overly sensitive

by  /  20 November 2014

Loss of MeCP2, the Rett syndrome gene, depletes immune cells throughout the bodies of mice, researchers reported yesterday at the 2014 Society for Neuroscience annual meeting in Washington, D.C.

1 Comment
News

Growth factor rescues neurons made from boys with Rett

by  /  18 November 2014

Neurons derived from the skin cells of boys with Rett syndrome can help screen potential treatments for the disorder, suggest unpublished results presented yesterday at the 2014 Society for Neuroscience annual meeting in Washington, D.C.

0 Comments
News

Growth factor shows promise for Phelan-McDermid syndrome

by  /  15 November 2014

Insulin-like growth factor improves social behavior and lessens repetitive behaviors in children with Phelan-McDermid syndrome, according to results from a preliminary clinical trial. Researchers presented the data yesterday at a satellite meeting of the 2014 Society for Neuroscience annual meeting in Washington, D.C.

14 Comments
News

Variants of autism-linked gene have diverse effects in mice

by  /  14 November 2014

Each of four different mutations in SHANK3, a leading autism candidate gene, leads to a different set of symptoms in mice, researchers have found. They presented their unpublished results on Thursday.

3 Comments