Mice with either too little or too much MeCP2, the gene mutated in Rett syndrome, show similar malfunctions in a learning and memory circuit.

Cells derived from the skin of boys and men with autism share a host of unusual characteristics.

Manipulating MeCP2, the gene mutated in Rett syndrome, has revealed two neuron types as crucial contributors to the condition.

Each of the various breathing difficulties seen in people with Rett syndrome may arise from a distinct circuit in the brainstem.

The anxiety and trouble with social skills seen in people with autism may originate outside of the brain, in neurons that govern touch.

MeCP2, a gene associated with neurodevelopmental conditions such as Rett syndrome and autism, has an unexpectedly essential role in mature brains.

Most symptoms of Rett syndrome stem from loss of the MeCP2 gene in just two types of neurons.

A drug that curbs the expression of MeCP2, a gene duplicated in people with an autism-linked syndrome, normalizes brain function and reverses abnormal behaviors in mice.