Tag: Phelan-McDermid syndrome

June 2014
Opinion / Viewpoint

How to evaluate new medications for autism

by  /  10 June 2014

There are no available medications for treating autism’s core symptoms, but there are several candidates in clinical trials. Jeremy Veenstra-VanderWeele describes the factors researchers must take into account when developing drugs for the disorder.

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April 2014
News

Clinical research: Autism-related syndrome changes with age

by  /  4 April 2014

Many characteristics of Phelan-McDermid syndrome — an autism-linked disorder arising from abnormalities at the tip of chromosome 22q13 — change as individuals age.

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January 2014
News

Mounting evidence implicates cerebellum in autism

by  /  6 January 2014

Results from four studies published in the past year point to a role for the cerebellum in autism-related behaviors.

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News

Genetics: Genes interact in autism-linked region

by  /  3 January 2014

Different combinations of genes located in an autism-linked section of chromosome 22 may modulate various symptoms, such as speech problems, large head size and low muscle tone, researchers reported 17 October in Genetics in Medicine.

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December 2013
News

Drug fixes cellular defects in autism-related disorder

by  /  2 December 2013

A new stem-cell model of Phelan-McDermid syndrome points to a possible treatment for the rare autism-related disorder, according to a study published in Nature.

3 Comments
November 2013
News

Jittery limb movements may predict autism subgroups

by  /  13 November 2013

Tiny fluctuations in the limb movements of children with autism can predict the severity of their condition and track their response to treatments, according to two unpublished studies presented at the 2013 Society for Neuroscience annual meeting in San Diego.

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News

Hormone reverses autism-like features in mouse model

by  /  11 November 2013

Insulin-like growth factor 2, a hormone involved in fetal growth, reverses abnormal social behaviors, repetitive behaviors and memory impairments in BTBR mice, a popular model of autism. The unpublished results were presented Monday at the 2013 Society for Neuroscience annual meeting in San Diego.

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July 2013
News

Study catalogs features of Phelan-McDermid syndrome

by  /  11 July 2013

The majority of people lacking a functional copy of the SHANK3 gene have both autism and severe intellectual disability, according to a study published 11 June in Molecular Autism.

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June 2013
News

Clinical research: Growth factor treats autism mouse model

by  /  21 June 2013

Insulin-like growth factor 1, a drug approved for use in children with short stature, reverses neurological deficits in mice with an autism-linked mutation in the SHANK3 gene, according to a study published 27 April in Molecular Autism. 

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May 2013
News

Parents turn their skills to furthering autism research

by  /  9 May 2013

Most parents educate themselves as much as possible when their child is diagnosed with a disorder. A handful of others — in many cases, mothers — have devoted their professional lives to research on autism-related disorders.

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