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Spectrum: Autism Research News

Tag: MRI

July 2022
A brain scan displays images of the amygdala with different sections highlighted in blue, red, orange and other colors.

Anxiety drives amygdala differences in autistic youth

by  /  27 July 2022

Regions of the brain’s fear center expand in autistic children and teenagers with anxiety, but not in their autistic or non-autistic peers without anxiety.

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June 2022
a grid of 9 brain maps showing activity in different areas of the brain

Brain networks diverge in autism by toddlerhood

by  /  8 June 2022

By as early as age 2, autistic children appear to have a smaller salience network and a larger default mode network, among other differences, than children without the condition.

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May 2022
MRIs

Growth charts map brain changes across lifespan

by  /  12 May 2022

The new resource is the first to chart human brain development from before birth to 100 years of age.

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White lab mice bunched up in corner of cage.

Mouse models mirror cerebellum patterns seen in autism

by  /  12 May 2022

Animals with different autism-linked mutations share disruptions to the mTOR signaling pathway, pointing to a potential molecular mechanism for the atypical cerebellar development seen in some autistic people.

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Color-coded brain images showing reduced thickness of superior frontal gyrus and other regions associated with presence of increased levels of inflammatory moleucle IL-6.

Inflammation may reshape brain regions tied to autism

by  /  6 May 2022

Having a genetic predisposition to inflammation is linked to structural changes in brain regions implicated in neurodevelopmental conditions.

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March 2022
Four 3D brains showing areas highlighted in green and purple.

Power shortages dim results of many neuroimaging studies

by  /  16 March 2022

An overreliance on small studies with limited reproducibility has slowed the advancement of neuroimaging, a new analysis suggests.

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November 2021

Synaptic overgrowth, hyperconnectivity may define autism subtype

by  /  18 November 2021

Model mice of the subtype also show hyperactivity in a signaling pathway called mTOR, bolstering the idea that distinct forms of autism have different biological roots and may require different treatment approaches.

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Dr. Audrey Brumback in her lab with her hair and lab coat flying out behind her.

Beyond the Bench: A conversation with Audrey Brumback

by  /  3 November 2021

Audrey Brumback riffs about volunteering in Mexico, having a lab next door to her husband’s and why she sometimes cries at work.

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September 2021
Four brains showing areas affected by the X chomosome in yellow

X chromosome exerts extra influence on brain development

by  /  15 September 2021

The X chromosome holds stronger-than-expected genetic sway over the structure of several brain regions. The genes that may underlie this oversized influence have ties to autism.

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Scientist Ethan Scott takes aim with a bow and arrow in his backyard.

Beyond the Bench: A conversation with Ethan Scott

by  /  13 September 2021

Ethan Scott packs his lab with math, physics and computer science experts to decode sensory brain networks in zebrafish models of autism.

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