Common genetic variants shape the structure of the cortex
A genome-wide association study lays a foundation for deeper investigation of these variants in neurodevelopmental conditions.
A genome-wide association study lays a foundation for deeper investigation of these variants in neurodevelopmental conditions.
The underlying regional neurobiology of the conditions may differ from person to person.
Brain scans of hundreds of infants suggest that up to 80 percent of those with autism have unusual amounts of cerebrospinal fluid. Researchers are studying how this might contribute to the condition.
Knocking down the gene that codes for the proteins normalizes the vocalizations.
The framework, inspired by the polygenic risk score, considers the cumulative effect of neuronal connections.
Few studies have tracked how brain structure and function change across adulthood in people with autism. Carper and her colleagues are collecting data to fill this gap.
Compared with their non-autistic peers, young autistic girls have a thicker cortex that thins more quickly with age.
Methodological choices and study-site artifacts confounded an attempt to replicate findings in support of an autism brain-imaging biomarker, according to new unpublished work.
Researchers know little about the ways genetic variants affect development in the infant brain. Knickmeyer, who launched the Organization for Imaging Genomics in Infancy, has spent the past five years trying to close the gap.
Using imaging methods to sort mouse models of autism may help identify subtypes of autistic people with similar underlying biology.