A genome-wide association study lays a foundation for deeper investigation of these variants in neurodevelopmental conditions.
Spectrum: Autism Research News
The underlying regional neurobiology of the conditions may differ from person to person.
Knocking down the gene that codes for the proteins normalizes the vocalizations.
The framework, inspired by the polygenic risk score, considers the cumulative effect of neuronal connections.
Few studies have tracked how brain structure and function change across adulthood in people with autism. Carper and her colleagues are collecting data to fill this gap.
Methodological choices and study-site artifacts confounded an attempt to replicate findings in support of an autism brain-imaging biomarker, according to new unpublished work.
Researchers know little about the ways genetic variants affect development in the infant brain. Knickmeyer, who launched the Organization for Imaging Genomics in Infancy, has spent the past five years trying to close the gap.
Using imaging methods to sort mouse models of autism may help identify subtypes of autistic people with similar underlying biology.