Rodent models of autism miss milestone in brain signaling
In mice exposed to maternal inflammation in the womb, a key chemical messenger never makes the switch from exciting brain signals to inhibiting them.
In mice exposed to maternal inflammation in the womb, a key chemical messenger never makes the switch from exciting brain signals to inhibiting them.
New results from brain scans of adults with autism are at odds with the popular theory that the condition involves weak brakes on brain activity.
Looking at the brain as a whole suggests that nudging flawed sets of neurons to collaborate better might alleviate autism traits.
How many cell types does the brain contain? Two new mouse studies bring scientists closer to the answer.
Novel sensors enable researchers to monitor the activity of two signaling chemicals in the brains of living fruit flies and mice.
Genes linked to autism are critical to the development of star-shaped brain cells called astrocytes, suggesting a key role for the cells in the condition.
Deleting one copy of a gene called MVP impairs the brain's ability to adapt to changes in the environment.
Researchers have repurposed the gene-editing tool CRISPR to dial down a gene’s activity in select subtypes of neurons in mice.
A fusion of two existing drugs alleviates autism-like features in a mouse model of the condition.
A widely used treatment for anxiety can eliminate some of the cognitive and social problems seen in mice missing a copy of ARID1B, a gene associated with autism.