Autistic children taking the drug showed improvements in some behaviors but not in their social skills.

Cannabidiol (CBD) blocks the action of a molecule that drives an overexcitability feedback loop in a rodent model of epilepsy.

Conventional optogenetic manipulations to excite or inhibit neurons stop when the light switches off. A new approach makes the changes last.

A new gene therapy approach for epilepsy tamps down neural activity on demand.

The in-depth approach shows mutations in the autism-linked gene disrupt neuronal growth and communication, as well as mitochondrial gene expression.

The circuit linking the prefrontal cortex and part of the thalamus is impaired in mice raised in social isolation and in mice with mutations in the FMR1 or TSC2 genes.

Iama Therapeutics is hoping a new class of molecule will prove successful against an old target in autism.

The drug quells seizures in children with Dravet syndrome or Lennox-Gastaut syndrome.

Long cast in supporting roles in the brain, astrocytes are now emerging as primary players in certain characteristics of autism and related conditions.

The catalog could help researchers understand the effects of autism-linked DNA variants that fall outside genes.