Tag: excitatory signaling

August 2018
News / Toolbox

Two new sensors track chemical signals in brains of living animals

by  /  24 August 2018

Novel sensors enable researchers to monitor the activity of two signaling chemicals in the brains of living fruit flies and mice.

0 Comments
April 2018
Opinion / Q&A

Autism genes assign starring role to support cells in brain

by  /  24 April 2018

Genes linked to autism are critical to the development of star-shaped brain cells called astrocytes, suggesting a key role for the cells in the condition.

0 Comments
March 2018
closeup of a mouse eye
News

Gene on chromosome 16 may be valuable player in autism

by  /  29 March 2018

Deleting one copy of a gene called MVP impairs the brain's ability to adapt to changes in the environment.

0 Comments
February 2018
colorful hands marking a path
News

Twist on gene-editing tool may speed studies of gene function

by  /  21 February 2018

Researchers have repurposed the gene-editing tool CRISPR to dial down a gene’s activity in select subtypes of neurons in mice.

0 Comments
January 2018
Mice lacking one copy of MEF2C have fewer neurons (red and green, right) in the hippocampus than controls do (left).
News

Modified Alzheimer’s drug may treat some forms of autism

by  /  18 January 2018

A fusion of two existing drugs alleviates autism-like features in a mouse model of the condition.

0 Comments
black rat and white rat
News

Anxiety drug reverses problems in mice with autism mutation

by  /  4 January 2018

A widely used treatment for anxiety can eliminate some of the cognitive and social problems seen in mice missing a copy of ARID1B, a gene associated with autism.

0 Comments
November 2017
magnetic stimulation of human brain
News

Magnetic stimulation bares imbalance of activity in fragile X brains

by  /  14 November 2017

Researchers have used transcranial magnetic stimulation to show that people with fragile X syndrome have weak ‘inhibitory’ signals, those that dampen neuronal activity in the brain.

0 Comments
lab mice
News

Fragile X behaviors may stem from gene’s loss in specific cells

by  /  13 November 2017

Deleting FMR1, the gene mutated in fragile X syndrome, in subsets of mouse neurons leads to distinct features of the condition.

0 Comments
Mice that lack UBE3A only in their inhibitory neurons are particularly susceptible to seizures.
News

Gene therapy technique prevents seizures in Angelman mice

by  /  12 November 2017

Introducing the gene UBE3A into neurons that dampen brain activity prevents seizures in a mouse model of Angelman syndrome.

0 Comments
October 2017
Microscope image of neuronal injections in brain.
News

Two drugs ease features of autism syndromes in mice

by  /  11 October 2017

Drugs that block certain brain enzymes could help treat two conditions associated with autism.

1 Comment