A young researcher faces down the skeptics.

The new tool may help researchers reconstruct the sequence of biological events that underlie development.

Strategies to replace or compensate for mutated copies of the TCF4 gene could lead to treatments for this profound form of autism, a new study suggests.

The DNA specific to mitochondria is difficult to access, but new methods place its secrets within reach.

A deactivated form of the gene editor restores UBE3A expression in mice and human neurons without cutting the genome. It may hold promise for future Angelman gene therapies.

Clues that problems with mitochondria contribute to autism have been accumulating for decades. In the past five years, a mutant mouse and a flurry of findings have energized the field.

Two new methods make it possible to delete long sections of the genome, expanding the reach of CRISPR gene editing.

A novel gene delivery system taps a protein found in people to encapsulate messenger RNA and transport it into cells.

Mutations in CUL3, a leading autism gene, may disrupt the movements of neurons during development; correcting this misdirection could lead to an autism therapy.

A new spin on the classic CRISPR gene-editing tool can alter the genome’s chemical tags and suppress gene expression for months.