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Spectrum: Autism Research News

Tag: CRISPR

October 2020
Ralf Schmid, the research director in Neurodevelopmental diseases at the Gene Therapy Program Orphan Disease Center, loads replicated mouse dna into wells in the gel before applying electric current to test the viability of the dna.

A quest for Quincy: Gene therapies come of age for some forms of autism

by ,  /  14 October 2020

A gene therapy for Angelman syndrome stands at the forefront of efforts to treat autism-linked conditions that stem from single genes.

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September 2020
Zebrafish embryos with various deformities.

CRISPR technique knocks down gene expression in animal embryos

by  /  2 September 2020

A new method that suppresses gene expression in the embryos of fish and mice may help researchers study autism genes in early development.

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November 2019
Micrograph of mouse brain showing transplanted human microglia

Chimeric mouse model aids study of brain’s immune cells

by  /  15 November 2019

A new technique allows researchers to transplant human microglia into mouse brains and better study the association between these cells and autism.

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Chromosomes swapping DNA

CRISPR technique tracks genetic activity in real time

by  /  8 November 2019

A new method scans gene expression in live cells and could help scientists study autism genes.

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October 2019

Gene-edited marmosets may mimic Rett syndrome traits

by  /  23 October 2019

Researchers have used the gene-editing tool CRISPR to disable the MECP2 gene in marmoset embryos. The six such marmosets created seem to recapitulate aspects of Rett syndrome.

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Two pairs of neurons shown in red.

Gene editing rids mice of DNA segment linked to autism

by  /  23 October 2019

Researchers have used a new gene-editing technique to delete a segment of DNA associated with autism and schizophrenia from mouse brain cells.

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CRISPR therapy may reverse autism mutation’s effects well past infancy

by  /  20 October 2019

Injecting the gene-editing tool CRISPR into the brains of mice may reverse the effects of an autism mutation at any age.

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Strand of DNA with one base letter highlighted.

DNA technique documents key events in cell history

by  /  18 October 2019

A new method uses mutations in DNA to maintain a detailed record of series of cellular events.

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Nobel predictions: Autism research may win big this year

by  /  4 October 2019

Forecasts for this year’s Nobel Prizes include several researchers whose work is relevant to autism.

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June 2019
Cells in a rat brain

CRISPR advances offer enhancements to gene-editing tool kit

by  /  7 June 2019

New versions of the DNA editor CRISPR enable scientists to turn off specific genes in rats, detect mutations in human tissue and delete segments of the genome.

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