Clues that problems with mitochondria contribute to autism have been accumulating for decades. In the past five years, a mutant mouse and a flurry of findings have energized the field.
Spectrum: Autism Research News
Two new methods make it possible to delete long sections of the genome, expanding the reach of CRISPR gene editing.
A novel gene delivery system taps a protein found in people to encapsulate messenger RNA and transport it into cells.
Mutations in CUL3, a leading autism gene, may disrupt the movements of neurons during development; correcting this misdirection could lead to an autism therapy.
A new spin on the classic CRISPR gene-editing tool can alter the genome’s chemical tags and suppress gene expression for months.
Mutations in any of 10 autism-linked genes in frogs lead to the same overabundance of brain cells that develop into neurons; the sex hormone estrogen lowers this excess.
Researchers have devised a new way of seeing how gene mutations affect cells during development.
A gene-editing treatment shows long-lasting effects in a mouse model of Angelman syndrome, a genetic condition related to autism.