Tag: CRISPR

November 2019
Micrograph of mouse brain showing transplanted human microglia
News / Toolbox

Chimeric mouse model aids study of brain’s immune cells

by  /  15 November 2019

A new technique allows researchers to transplant human microglia into mouse brains and better study the association between these cells and autism.

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Chromosomes swapping DNA
News / Toolbox

CRISPR technique tracks genetic activity in real time

by  /  8 November 2019

A new method scans gene expression in live cells and could help scientists study autism genes.

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October 2019
News

Gene-edited marmosets may mimic Rett syndrome traits

by  /  23 October 2019

Researchers have used the gene-editing tool CRISPR to disable the MECP2 gene in marmoset embryos. The six such marmosets created seem to recapitulate aspects of Rett syndrome.

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Two pairs of neurons shown in red.
News

Gene editing rids mice of DNA segment linked to autism

by  /  23 October 2019

Researchers have used a new gene-editing technique to delete a segment of DNA associated with autism and schizophrenia from mouse brain cells.

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News

CRISPR therapy may reverse autism mutation’s effects well past infancy

by  /  20 October 2019

Injecting the gene-editing tool CRISPR into the brains of mice may reverse the effects of an autism mutation at any age.

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Strand of DNA with one base letter highlighted.
News / Toolbox

DNA technique documents key events in cell history

by  /  18 October 2019

A new method uses mutations in DNA to maintain a detailed record of series of cellular events.

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News

Nobel predictions: Autism research may win big this year

by  /  4 October 2019

Forecasts for this year’s Nobel Prizes include several researchers whose work is relevant to autism.

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June 2019
Cells in a rat brain
News / Toolbox

CRISPR advances offer enhancements to gene-editing tool kit

by  /  7 June 2019

New versions of the DNA editor CRISPR enable scientists to turn off specific genes in rats, detect mutations in human tissue and delete segments of the genome.

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April 2019
Human fetus with molecules going into it's brain
News

Injecting CRISPR into fetal brain may correct autism mutations

by  /  24 April 2019

Researchers are edging closer to a therapy for Angelman syndrome — a condition related to autism — that involves injecting the gene-editing enzyme CRISPR into the fetal brain.

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portrait of Dr. Lilia Lakoucheva
Opinion / Q&A

Beyond the bench: A conversation with Lilia Iakoucheva

by  /  16 April 2019

Lilia Iakoucheva spends her days running outdoors and solving the molecular complexities of autism, sometimes at the same time.

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