Notable papers in autism research in 2018
This year’s list of top papers highlights new dimensions in our understanding of autism genetics and hints at novel treatments.
This year’s list of top papers highlights new dimensions in our understanding of autism genetics and hints at novel treatments.
Scientists used the gene-editing tool CRISPR to create two marmosets lacking MECP2, the gene mutated in Rett syndrome.
A protein proves crucial to spatial memory in mice, genes in the 16p11.2 chromosomal region interact in fruit flies’ eye development, and having more autism features tracks with decreased responsiveness to direct gaze.
A miniature particle delivers the gene-editing tool CRISPR into the brains of fragile X mice.
Autism and intelligence share genetic variants, researchers grow Neanderthal mini-brains and see overlap with autism, and maternal diabetes is an autism risk factor.
Four new techniques expand the repertoire of the gene editor CRISPR.
Benefits of diets for autism features remain unproven, variants of the same DNA region make brains big or small, and STAT announces a new CRISPR tracker.
Watch the complete replay of Feng Zhang discussing current genome editing technologies and the future of these tools.
The gene-editing tool CRISPR may cause thousands of off-target mutations, but critics say it’s way too soon to accuse it of infidelity.
A checklist for fragile X syndrome could help identify people with the condition in low-resource settings, France unveils a plan for early diagnosis and education of children with autism, and virally inserted ‘bar codes’ help track individual neurons.