Tag: common variants

October 2018
Two children picking mushrooms in a field.
News

Genetics plays outsized role in autism, large study shows

by  /  15 October 2018

Autism is more heritable than anorexia, alcohol dependence, depression and obsessive-compulsive disorder, according to an analysis of data from nearly 4.5 million people.

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DNA helix with two mutations glowing blue on the helices. Rebecca Horne
News

Study links subset of genetic variants to autism, intellectual disability

by  /  3 October 2018

Genetic variants across the genome contribute to about 8 percent of the risk for certain developmental conditions — much more than previously thought.

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September 2018
A collage of a DNA helix with two of the bars showing a different color. by Rebecca Horne
News

Control of gene expression alters impact of autism mutations

by  /  27 September 2018

Variants that control gene expression are often involved in whether a mutation ends up being harmful, and how harmful it is.

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DNA twisting in black space
News / Toolbox

Two tools speed the search for mutations in whole genomes

by  /  14 September 2018

Software to identify genetic variants, along with a new synthetic human genome, could help scientists discover mutations associated with conditions such as autism.

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August 2018
Multimedia / Webinars

Journal club: Rare genetic variation in brain conditions

6 August 2018

Watch the complete replay of this journal club, which featured a paper exploring rare genetic variation in psychiatric conditions, including autism.

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April 2018
Opinion / Viewpoint

For accurate results in autism, genetic databases need diversity

by ,  /  10 April 2018

We must diversify databases of reference DNA to improve our ability to interpret the consequences of genetic variation.

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March 2018
Opinion / Viewpoint

Explaining ‘resilience’ in autism may seed new therapies

by  /  27 March 2018

Some individuals who have autism mutations show no signs of the condition; understanding why may lead to treatments.

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February 2018
Short video of the words "autism" changing to "ADHD"
Features / Deep Dive

Decoding the overlap between autism and ADHD

by  /  7 February 2018

Autism and attention deficit hyperactivity disorder often coincide, but the search for common biological roots has turned up conflicting evidence.

5 Comments
January 2018
illustration of DNA strand
News

Variant analysis may vastly underestimate heritability of autism behaviors

by  /  29 January 2018

Existing genome scans do not detect many of the DNA variants that underlie behavioral problems.

3 Comments
black rat and white rat
News

Anxiety drug reverses problems in mice with autism mutation

by  /  4 January 2018

A widely used treatment for anxiety can eliminate some of the cognitive and social problems seen in mice missing a copy of ARID1B, a gene associated with autism.

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