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Spectrum: Autism Research News

Tag: common variants

September 2023

Common genetic variants shape the structure of the cortex

by  /  18 September 2023

A genome-wide association study lays a foundation for deeper investigation of these variants in neurodevelopmental conditions.

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Research image of organoids in the forebrain.

Head size parts autism into two major subtypes

by  /  12 September 2023

An imbalance in the number of excitatory neurons in early brain development may account for the difference.

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July 2023
Blurry photograph of a crowd of people on a street.

Some who lack autism diagnosis carry variants tied to the condition

by  /  13 July 2023

The variants are associated with slight differences in measures of intelligence, income and employment, but the relationship may not be causal.

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May 2023
Composite research image of organoids at several stages of development.

Genetic background sways effects of autism-linked mutation

by  /  18 May 2023

Experiments offer clues to why certain mutations are associated with autism in some people and not others.

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December 2022
X chromosome against a dark background.

Common and rare autism-linked variants share functional effects

by  /  1 December 2022

Within the 16p region of the genome, the two types of variants similarly decrease neuronal gene expression — an effect that may reflect their spatial relationship.

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November 2022
Photograph of a parent crossing a city street with two children

A mix of common and rare variants shapes autism inheritance patterns

by  /  4 November 2022

The study also reveals a link between language development and common variants.

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October 2022
Conceptual illustration of two DNA helixes with several overlapping portions showing common and differing genes.

Genome scan spots common variant differences between autism and ADHD

by  /  12 October 2022

Common variants in five regions of the genome may determine whether someone has one condition versus the other.

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August 2022
A pregnant woman and another figure are obscured by shadows.

Maternal genetics may confound studies of autism’s link to prenatal factors

by  /  2 August 2022

Women who carry genetic variants tied to autism have an elevated chance of experiencing pregnancy-related events linked to the condition in their children.

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June 2022
Illustration of two figures in a field of black circles representing genetic risks. The circles surround the figure on the left and stay farther away from the figure on the right.

Common inherited variants tied to autism show sex bias in families

by  /  23 June 2022

Siblings of autistic females are more likely to have autism than siblings of autistic males are, and mothers of autistic children carry more common, autism-linked variants than fathers do.

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A street crowded with pedestrian traffic

Spectrum of variants contribute differently to autism traits

by  /  3 June 2022

Different combinations of common, rare, inherited and spontaneous mutations may explain why traits vary so widely among autistic people.

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