An online catalog helps clarify the roles of thousands of spontaneous mutations in four neuropsychiatric disorders, including autism.

A new technique allows researchers to trace the location and measure expression levels of hundreds of genes in individual cells. The method, described 9 April in Science, could reveal networks of genes with relevance to autism.

In a feat that unites findings from 2,800 experiments in more than 100 types of cells, researchers have mapped the human epigenome — the many layers of code that turn genes on or off.

A new study maps the many targets of the autism gene TBR1, but it’s just one small piece of a much bigger picture.

A new resource maps the expression of nearly 17,000 proteins in a range of tissues throughout the human body.

A new tool helps predict whether large DNA duplications and deletions, common among people with autism, are harmful or benign.
 

A rare form of autism linked to a duplication of the 15q11-13 chromosomal region shares a molecular signature with more common forms of the disorder, suggests unpublished research presented yesterday at the 2014 Society for Neuroscience annual meeting in Washington, D.C.

A new database bridges the gap between candidate genes identified by sequencing studies and mouse models that can help reveal the genes’ role in various disorders. Researchers presented the tool today at the 2014 Society for Neuroscience annual meeting in Washington, D.C.

Leaders from the National Institutes of Health and Nature Publishing Group say an array of simple reforms can boost the reliability of research findings. Their suggestions spurred a lively audience discussion yesterday at the 2014 Society for Neuroscience annual meeting in Washington, D.C.

Analyzing the sequences of more than 20,000 people, researchers have unearthed the largest and most robust list of autism genes so far, they reported today in Nature.