Gut microbiome meta-analysis reveals consistent autism signal
But the field needs to move on from cross-sectional studies to gain insights into the causes and consequences of the association, experts say.
But the field needs to move on from cross-sectional studies to gain insights into the causes and consequences of the association, experts say.
Exposing neurons to valproic acid, a well-known environmental risk factor for autism, disrupts their ability to generate different proteins from the same gene.
Psychiatric genomics promises to shed light on the genetic basis of autism, but it’s vital to include Africa in this research, Iyegbe and Okewole say.
The catalog of rare copy number variants tied to autism and other conditions could help researchers identify which genes account for the mutations’ effects.
Researchers have long studied subgroups of people who share genetic variants, but the newly formed ‘CNV Commission’ is also looking at people with shared traits across different neurodevelopmental conditions.
Swiss biotech Stalicla hopes to bring precision medicine to autism. Experts praise efforts to identify autism subgroups, but evidence to support the company’s claims has yet to be seen.
Autism may involve different levels of RNA isoforms encoded by genes in the brain, which express many more proteins than previously thought.
Thousands of protein-protein interactions mapped in mice reveal how these networks shift across seven kinds of tissue.
A large, whole-genome sequencing study of families yields insights into ultra-rare genetic variants that contribute to autism.
Next-generation machine-learning tools are poised to upend how scientists study behavior in animal models of autism — and not everyone is happy about it.