Subtle language
We now know that people with autism have a much broader range of language ability than previously thought. How can we measure subtle language deficits in this group?
We now know that people with autism have a much broader range of language ability than previously thought. How can we measure subtle language deficits in this group?
Heavier newborns have larger brains later in life, and a larger cerebral cortex — the brain region responsible for high-level functions such as consciousness and language. The findings, published 19 November in the Proceedings of the National Academy of Sciences, are the first to assess birth weight’s connection to brain development.
‘Hyperscanning,’ a set of techniques for simultaneously measuring brain activity in two people, is yielding insights into autism.
Loss of one copy of TBR1, an autism-linked gene involved in fetal brain development, leads to brain malformations, according to a study published in the September issue of Molecular Syndromology.
Two new studies that follow the development of children with autism suggest that distinct subgroups of the disorder exist early on, and that the severity of symptoms in most of these children remains stable over time.
Researchers have developed a method to fix and stain intact mouse brains for electron microscopy, according to a study published 21 October in Nature Methods. The technique allows them to trace the paths of neurons as they project across the brain.
An autism-linked protein called CASPR2 promotes the development of dendrites, the bushy structures atop neurons that receive signals from other neurons, according to a study published 30 October in Proceedings of the National Academy of Sciences. Lowering CASPR2 levels leads to sparse dendrites and few synapses, the junctions between neurons.
There’s little rigorous evidence on whether animals help people with autism become more sociable, or which people with the disorder might benefit the most.
Recent findings beg a critical question: Should clinical genetics labs make their databases available for research?
Nearly half of children with malformation of the corpus callosum, which links the two hemispheres of the brain, have symptoms of autism, according to a study published 5 October in the Journal of Autism and Developmental Disorders.