Tag: sequencing

May 2018
Diagram statistics
News

Analysis of sequences pegs 99 top autism genes

by  /  10 May 2018

The number of top autism genes has risen from 65 to 99, based on an analysis of nearly 35,000 sequences. And researchers are seeing the first hints of autism risk variants in the regions between genes.

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News

Hunt for autism variants between genes comes up empty

by  /  7 May 2018

To find variants between genes that contribute to autism, researchers may need thousands more whole genomes than they have now.

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April 2018
four scientists standing on colorful tile
News

CRISPR goes wild, and scientists debate its fidelity

by  /  30 April 2018

The gene-editing tool CRISPR may cause thousands of off-target mutations, but critics say it’s way too soon to accuse it of infidelity.

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genetic code sequences
News / Toolbox

Map of DNA variation identifies key genetic regions

by  /  20 April 2018

A new analysis of the genomes of more than 11,000 people reveals regions that have few mutations, indicating they have important functions.

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father and son standing on the beach during sunset
News

Some mutations tied to autism may be passed down from fathers

by  /  19 April 2018

Some children with autism inherit rare mutations in noncoding DNA from their unaffected fathers.

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March 2018
water droplets contain and concentrate the materials needed to synthesize genes.
News / Toolbox

New tools speed genome assembly, tests of gene function

by  /  23 March 2018

Two new techniques could help reveal the molecular basis of conditions such as autism.

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Neurons from mice missing OTUD7A (right) have fewer spines than do those from controls (left).
News

Studies pinpoint key gene in region linked to autism

by  /  21 March 2018

A single gene, OTUD7A, may account for most of the features seen in people missing a segment of chromosome 15 known as 15q13.3.

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February 2018
More than 4,000 types of brain cells show distinct gene expression patterns.
News / Toolbox

Map of gene expression gives new clues to brain development

by  /  23 February 2018

A new map that analyzes gene expression one cell at a time shows how various cell types mature and form the brain’s distinctive structures.

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marker genes in cells
News / Toolbox

New databases decode gene expression in brain cells

by  /  2 February 2018

Researchers have generated two new databases that catalog which genes are expressed in specific brain cells.

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December 2017
Features / Special Reports / 2017: Year in review

Notable papers in autism research in 2017

22 December 2017

This year’s list of top papers highlights nuances in the genetics of autism and new leads on early treatment.

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