Tag: sequencing

November 2017
brain cells and microglia
News

Map of microglia in mouse brain may reveal role in autism

by  /  15 November 2017

Researchers have mapped how immune cells in the brain called microglia change with age in mice.

1 Comment
October 2017
Medical practitioner marking blood sample.
News

Mosaic mutations in sperm point to increased autism risk

by  /  23 October 2017

More than 5 percent of mutations thought to have arisen spontaneously in a child with autism may in fact be inherited.

1 Comment
A new resource charts the locations of two types of chemical modifications to chromosomes (top, middle) and gene expression changes (bottom) in brain tissue.
News / Toolbox

Databases describe DNA ‘dials’ that control gene expression

by  /  20 October 2017

Two new resources catalog how genetic variants affect gene expression in the brain.

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Week of OctoberOct
9th
2017
News / Spotted

Maternal multivitamins; vaccine retraction; simultaneous schizophrenia and more

by  /  13 October 2017

Taking prenatal multivitamins may reduce the risk of having a child who has autism with intellectual disability, another vaccine-autism link study is being retracted, and schizophrenia sometimes accompanies autism.

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A new method analyzes gene expression to identify more than a dozen cell types in human brain tissue.
News / Toolbox

Droplet technique probes gene expression in brain tissue

by  /  6 October 2017

A new method offers an efficient way to examine gene expression in individual cells from postmortem brains.

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September 2017
Week of SeptemberSep
18th
2017
News / Spotted

Genetic hotspot; big brain collaboration; funding fall and more

by  /  22 September 2017

A gene called TRIO may be a hotbed for autism mutations, an international collaboration focuses on the whole brain and one behavior, and Autism Speaks cuts grant spending.

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Illustration of DNA in cross stitch pattern
News

Sizeable fraction of autism risk traced to ‘mosaic’ mutations

by  /  14 September 2017

Mutations that appear in only some of the body’s cells contribute to autism in about 4 percent of people with the condition.

3 Comments
Week of SeptemberSep
4th
2017
News / Spotted

Face learning; mosaic inheritance; nosy scientists and more

by  /  8 September 2017

A monkey study suggests facial recognition is not innate, a puzzle piece symbol carries negative connotations, and scientists are using a federal law to snoop on colleagues.

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August 2017
A young boy and a young girl hiding behind the kitchen table.
News

Sibling study bolsters role of common variants in autism

by  /  24 August 2017

Children with autism are genetically more similar to one another than to a group of unaffected siblings.

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A family holding hands and walking down the sidewalk.
News / Toolbox

Whole genomes may power search for autism risk factors

by  /  23 August 2017

Scientists this week announced the release of nearly 7,000 whole-genome sequences from a collection of families that each have one child with autism.

1 Comment