Long cast in supporting roles in the brain, astrocytes are now emerging as primary players in certain characteristics of autism and related conditions.
Spectrum: Autism Research News
A handful of scientists are committed to advancing research on the autism-related genetic conditions their own children have.
The approach, tested in mice, selectively boosts the expression of the autism-linked gene SCN1A in a subgroup of inhibitory cells.
Interneurons that fail to propagate electrical signals in mice that model Dravet syndrome may cause the animals, like people with the autism-linked condition, to die suddenly.
The animals recall fear more readily if a set of inhibitory neurons in the hippocampus is switched on.
Mutations in the autism-linked gene PAX5 underlie a range of traits, including developmental delay, intellectual disability, seizures and autism.
The protein, FMRP, shapes cell signaling near synapses but switches to regulate genes in the cell body, according to new research.
Cannabis-derived drugs are approved to treat only a small number of autism-related conditions, but many autistic people and their families experiment with medical marijuana to ease autism traits. In this special report, Spectrum rounds up what the science says about cannabis and autism.
Dysfunctional circuits and a rogue sodium channel in the brainstem may explain the disordered breathing pattern seen in children with Pitt-Hopkins syndrome, a form of autism.
Altered electrical activity in the neurons of mice with a mutated copy of SCN2A may explain the animals’ autism-like social behaviors.