The collection offers a glimpse into differences in cell composition — across people and brain regions — that may shape neural function.
Spectrum: Autism Research News
The findings in rhesus macaque monkeys may provide clues to sex differences in the heredity of social behavior in people.
Here is a roundup of news and research for the week of 26 June.
The result raises hopes for an ongoing clinical trial in people — and offers fresh insight into the biology of imprinting and the UBE3A antisense transcript.
Having an infection during pregnancy is tied to a small increase in the chances of having an autistic child, but the connection may not be causal.
Findings on microglia and other brain cell types bolster the animal’s validity as a model system for the condition.
Roche’s gene therapy drug Rugonersen boosts expression of the protein missing in the syndrome in mice and monkeys, but whether it works in people remains to be seen.
People’s brains have a larger network of inhibitory interneurons than mouse brains do, according to a new study. Changes to that network could contribute to autism or other conditions, says lead investigator Moritz Helmstaedter.
The approach, tested in mice, selectively boosts the expression of the autism-linked gene SCN1A in a subgroup of inhibitory cells.
For decades, many researchers who study nonhuman primates kept quiet about their work, concerned about the extreme actions taken by some animal welfare activists. But a growing number are speaking more openly about the importance of their work in an attempt to take back the narrative.