Motor differences are more relevant than has historically been appreciated for understanding, assessing and supporting people on the spectrum.
Spectrum: Autism Research News
Tag: developmental delay
The questionnaires used to screen for autism are far from perfect, and tweaking them may not be enough. Roald Øien wants researchers to find better solutions.
Developmental delay, intellectual disability and behavioral issues are common among people who have mutations in MYT1L, a gene with strong ties to autism.
Dysfunctional circuits and a rogue sodium channel in the brainstem may explain the disordered breathing pattern seen in children with Pitt-Hopkins syndrome, a form of autism.
Compared with a previous mouse strain, a new model better reflects some of the difficulties that people with a rare autism-related syndrome experience, and may help identify biomarkers of the syndrome.
The algorithm estimates a child’s likelihood of having autism from patterns of co-occurring conditions in electronic health records, outperforming a widely used screening test.
Many genes linked to autism, schizophrenia and neurodevelopmental delay regulate gene expression and support communication between neurons.
Researchers have rated more than 17,000 genes, including many linked to autism and other neuropsychiatric conditions, according to their sensitivity to deletions and duplications.
Autistic people with at least one sibling make greater gains in adaptive functioning than their only-child counterparts do.
Mutations in genes that encode a histone, which gives structure to chromosomes, can lead to developmental delay and congenital anomalies.