Tag: BTBR mice

March 2018
illustration of mouse on sale in a city
News

‘Outmoded’ mouse models of autism may still yield new advances

by  /  21 March 2018

Many researchers question the value of three early mouse models of autism, but the models have their staunch supporters.

0 Comments
June 2015
Multimedia / Webinars

William Catterall examines anxiety drugs for autism

24 June 2015

Watch the complete replay of William Catterall explaining how low doses of an anxiety drug alleviate autism-like symptoms in mice.

5 Comments
April 2015
Opinion

Mouse studies support second chance for fragile X drug

by  /  28 April 2015

Two new studies give a boost to arbaclofen, which failed to meet expectations in clinical trials for autism and fragile X syndrome.

6 Comments
October 2014
Opinion / Cross Talk

How early should autism treatment begin?

by  /  15 October 2014

The preliminary success of a therapy designed to help infants with symptoms of autism raises broader questions about the potential promise and many challenges of early intervention.

8 Comments
September 2014
Opinion / Viewpoint

Optimizing behavioral assays for mouse models of autism

by  /  23 September 2014

As the number of autism rodent models climbs, it is a good time for the field to step back and consider the best practices for assessing autism-like symptoms in rodents, says Jacqueline Crawley.

3 Comments
August 2014
News

Signaling imbalance skews sensory responses in autism mice

by  /  11 August 2014

Mice modeling autism have trouble integrating different kinds of sensory information such as sight, sound and touch. A study published 31 July in Neuron reports that an imbalance between signals that calm neurons and those that excite them leads to these sensory problems.

1 Comment
April 2014
News

Low-dose sedative eases autism symptoms in mice

by  /  3 April 2014

The equivalent of one-tenth of a single pill of the anxiety drug clonazepam alleviates many autism-like behaviors in a mouse model of the disorder, according to a study published 19 March in Neuron.

9 Comments
February 2014
News / Toolbox

Automated tool records behavior of autism mouse models

by  /  5 February 2014

A new tracking system automatically logs and scores mouse behavior as well as a human observer does, according to a paper published 31 December 2013 in Journal of Neuroscience Methods.

0 Comments
January 2014
News

Cognition and behavior: Drug ups sociability in autism mice

by  /  31 January 2014

Rapamycin, a drug given to suppress immune rejection after transplants, improves social behavior in mice with features of autism, reports a study published in the January issue of Brain Research Bulletin.

0 Comments
November 2013
News

Compendium of mouse brains highlights autism’s diversity

by  /  14 November 2013

By mapping the brains of not 1 but 27 mouse models of autism, researchers are making sense of the widely divergent structural changes seen in autism brains, they reported Wednesday at the 2013 Society for Neuroscience annual meeting in San Diego.

0 Comments