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Spectrum: Autism Research News

Tag: autism

March 2023
Still image showing activity of activity of neurons with genetic mutations in the 15q11-13 chromosomal region.

Single gene insufficient to account for dup15q, Angelman traits

by  /  21 March 2023

UBE3A, a key gene associated with both autism-linked conditions, can explain most — but not all — of the syndromes’ atypical neuronal properties.

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Three groups of people meet and mix at a crossroads.

Letter to the editor: Researchers must bridge disconnect at ‘autism crossroads’

Two groups of researchers respond to Spectrum’s article about the power struggle among researchers, self-advocates and families, calling on their autistic and non-autistic colleagues to work collaboratively and promote equity in autism research.

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Speech bubble formed by a network of communication

Community Newsletter: Tracing fruit fly, human connectomes

by  /  19 March 2023

Researchers took to Twitter this week to discuss the most complete map of brain structure to date — that of a larval fruit fly — and the largest-yet human brain connectivity resource.

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Week of MarchMar
13th
2023

Spotted around the web: Brain imaging replicability; CRISPR-edited neurons; sex-based variability in mice

by , ,  /  17 March 2023

Here is a roundup of news and research for the week of 13 March.

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Wearable device records, stimulates single neurons in people on the go

by  /  17 March 2023

The tool connects to electrodes implanted in people with epilepsy or other brain conditions and can monitor and regulate neurons during everyday activities.

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Illustration of hybrid objects: part light bulb, part lab vial, some in blue and some in red to signify null and replicated results.

Null and Noteworthy: Registered reports; motor measurements; viral DNA

by  /  16 March 2023

In this edition of Null and Noteworthy, Spectrum talks with a Nature editor about the journal’s move to publish more null results.

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Drop of liquid medicine with air bubbles is dripping from a pipette on a light pink background.

FDA approval of trofinetide may spur further drug development for Rett

by  /  16 March 2023

The drug, welcomed by patients, might be just the first of many.

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Image of scientists working in a lab.

African genetics study NeuroDev shares initial findings

by  /  15 March 2023

The most comprehensive study of neurodevelopmental conditions in Kenya and South Africa ever conducted shares preliminary results and lessons.

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Photograph of a doctor taking notes on a toddler who is playing with their mother.

Journal Club: Meta-analysis oversells popular autism screen

by  /  14 March 2023

The Modified Checklist for Autism in Toddlers (M-CHAT) accurately flags autistic toddlers, a new systematic review and meta-analysis suggests, contrary to past evidence that the tool’s validity varies depending on a child’s age and traits. Experts weigh in on the discrepancy.

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MRI scan with a section enlarged to display the scan's grey-white boundary.

Brain imaging do-over offers clues to field’s replication problem

by  /  13 March 2023

Methodological choices and study-site artifacts confounded an attempt to replicate findings in support of an autism brain-imaging biomarker, according to new unpublished work.

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