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Spectrum: Autism Research News

Tag: valproic acid

February 2023
Illustration of neurons.

Chromatin remodeling tied to altered splicing in autism model

by  /  7 February 2023

Exposing neurons to valproic acid, a well-known environmental risk factor for autism, disrupts their ability to generate different proteins from the same gene.

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August 2022
A pregnant woman and a doctor, both masked, have a conversation in an examination room.

U.K. health authority investigates epilepsy drug’s link to autism

by  /  30 August 2022

Prenatal exposure to topiramate increases a child’s autism odds, according to the study that prompted the inquiry, but experts caution that pregnant people with epilepsy have few other options for controlling seizures.

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January 2019
Rat neurons

Rat model of autism shows unusual brain growth at birth

by  /  30 January 2019

The brains of rats exposed in utero to the seizure drug valproate show a significant increase in brain size around the time of birth.

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December 2018
Siblings, a baby and a toddler, play together at home.

How pregnancy may shape a child’s autism

by  /  5 December 2018

Autism is predominantly genetic in origin, but a growing list of prenatal exposures for mother and baby may sway the odds.

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June 2018

New restrictions on epilepsy drug may do more harm than good

by  /  21 June 2018

A partial ban in Europe on the use of a drug called valproate during pregnancy could deny women effective treatment for serious conditions.

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Baby chick on white background.

Chick model of epilepsy-drug exposure may mimic signs of autism

by  /  1 June 2018

Exposing fertilized chicken eggs to valproic acid, an epilepsy drug, yields chicks with apparent social deficits.

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April 2018
Week of AprilApr
23rd
2018

New journal; organoid ethics; acetaminophen association and more

by  /  27 April 2018

A journal covering autism in adulthood makes its debut, researchers call for an ethical framework for human organoid studies, and the association between acetaminophen and autism risk comes under scrutiny.

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February 2018
Week of FebruaryFeb
19th
2018

Fake autism claim; knocking out anesthesia; haunting milestone and more

by  /  23 February 2018

Despite social media rumors, a British children’s television show does not cause autism; childhood anesthesia is not tied to autism risk; and an adult on the spectrum reaches a haunting milestone

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November 2017
white lab rats piled together

Rodent ratings reveal periods of vulnerability to harmful exposures

by  /  13 November 2017

Nongenetic rodent models most relevant to autism tend to be those exposed to environmental agents in the womb or shortly after birth.

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mouse with a sensor connected to brain

Three autism mouse models marked by defects in same circuit

by  /  8 November 2017

Problems with social interactions stem from faulty wiring of a single circuit spanning distant brain regions, results from three mouse models of autism suggest.

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