Tag: GABA

July 2019
group of dark furred lab mice huddling together.
News

Mutations tied to autism may alter gut function, microbiome in mice

by  /  11 July 2019

Mutations in the autism gene NLGN3 may alter the gut nervous system of mice.

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May 2019
News

Gut microbes from autistic children may alter behavior in mice

by  /  30 May 2019

Mice colonized with gut microbes from some autistic boys show behaviors like those of the boys.

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News

The signaling imbalance theory of autism, explained

by  /  1 May 2019

The signaling imbalance theory holds that the brains of autistic people are hyper-excitable because of either excess neuronal activity or weak brakes on that activity.

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January 2019
Rat neurons
News

Rat model of autism shows unusual brain growth at birth

by  /  30 January 2019

The brains of rats exposed in utero to the seizure drug valproate show a significant increase in brain size around the time of birth.

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November 2018
Two hands hold two pills, one red and one blue.
News

Drug duo delivers brain, behavioral benefits for fragile X syndrome

by  /  8 November 2018

Administering a cholesterol drug alongside an antibiotic eases atypical behavior and restores the signaling balance in the brains of people with fragile X syndrome.

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Chandelier cells send their signals through fibers arranged in vertical columns that are reminiscent of the candles in a chandelier.
News

Chandelier cells may sprout few branches in autism brains

by  /  7 November 2018

Specialized neurons called chandelier cells, which dampen brain signals, make unusually few connections in the brains of people with autism.

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Neurons glow green in mice brain.
News

Loss of autism gene alters landscape of inhibitory brain signals

by  /  6 November 2018

Mice lacking one copy of a leading autism gene have hyperexcitable brains and problems with learning and memory.

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Outlines of mice neurons have long branches.
News

Rodent models of autism miss milestone in brain signaling

by  /  4 November 2018

In mice exposed to maternal inflammation in the womb, a key chemical messenger never makes the switch from exciting brain signals to inhibiting them.

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October 2018
News

Study calls into question chemical messenger’s role in autism

by  /  29 October 2018

New results from brain scans of adults with autism are at odds with the popular theory that the condition involves weak brakes on brain activity.

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September 2018
Mouse brain photograph shows the area of drug delivery highlighted in red.
News / Toolbox

Brain implant mutes seizure-like activity in mice

by  /  28 September 2018

A new brain implant pumps chemical signals directly into a target region to ease seizure-like activity in mice.

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