Tag: GABA

February 2018
colorful hands marking a path
News

Twist on gene-editing tool may speed studies of gene function

by  /  21 February 2018

Researchers have repurposed the gene-editing tool CRISPR to dial down a gene’s activity in select subtypes of neurons in mice.

0 Comments
January 2018
By staining the nuclei from all cells blue (left) and those from neurons red (middle), researchers can isolate the resulting purple nuclei from neurons (right).
News

Chemical tags on genomes in neurons altered in autism brains

by  /  31 January 2018

Neurons from people with autism may have an unusual pattern of chemical tags that turn genes on and off.

1 Comment
black rat and white rat
News

Anxiety drug reverses problems in mice with autism mutation

by  /  4 January 2018

A widely used treatment for anxiety can eliminate some of the cognitive and social problems seen in mice missing a copy of ARID1B, a gene associated with autism.

0 Comments
November 2017
Mice that lack UBE3A only in their inhibitory neurons are particularly susceptible to seizures.
News

Gene therapy technique prevents seizures in Angelman mice

by  /  12 November 2017

Introducing the gene UBE3A into neurons that dampen brain activity prevents seizures in a mouse model of Angelman syndrome.

0 Comments
October 2017
Microscope image of neuronal injections in brain.
News

Two drugs ease features of autism syndromes in mice

by  /  11 October 2017

Drugs that block certain brain enzymes could help treat two conditions associated with autism.

1 Comment
August 2017
Week of AugustAug
7th
2017
News / Spotted

Off-key outcomes; visualizing variants; urine indifference and more

by  /  11 August 2017

Music therapy proves ineffective for autism, brain structures differ with 16p11.2 duplications and deletions, and mice missing NLGN3 may influence the sociability of their littermates.

2 Comments
News

Flash of light shifts social behavior in autism mice

by  /  2 August 2017

Turning on a set of neurons that dampen brain activity improves social behavior in a mouse model of autism; turning off neurons that excite brain activity does the same thing.

2 Comments
July 2017
News

Drug that shifts brain’s signaling balance could treat autism

by  /  20 July 2017

A drug that alters the balance of two key chemical messengers in the brain may help treat autism, suggests a proof-of-principle study.

1 Comment
May 2017
News

Hallucinations unusually common in adults with autism

by ,  /  24 May 2017

Negative experiences, such as being bullied or socially isolated, may lead to hallucinations.

3 Comments
News

Altered circuit may underlie repetitive behaviors in autism

by  /  13 May 2017

A brain circuit that controls movement is altered in people with autism, a postmortem brain study suggests.

2 Comments
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