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Tag: GABA

July 2021
Immature inhibitory cells surround mature neuron.
News

Critical time window flagged for autism gene’s influence

by  /  16 July 2021

A transplant of inhibitory neurons during the second week of life prevents social difficulties and a brain signaling imbalance in mice missing a copy of FOXG1.

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May 2021
News

Stimulant restores cell signaling, eases behavior issues in animals missing autism gene

by  /  28 May 2021

Worms and zebrafish missing both copies of the gene CHD7 have disrupted cellular signaling, a dearth of inhibitory neurons and behavior changes — all of which are reversed by the stimulant drug ephedrine.

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News

Autism-related conditions linked to altered visual perception

by  /  5 May 2021

A test of binocular rivalry may distinguish between autism subtypes and help researchers screen the efficacy of certain drugs.

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April 2021
Brain scan showing communication from amygdala to hypothalamus about social reward.
News

Brain circuit makes social interactions rewarding, may be altered in autism

by  /  30 April 2021

Blocking connections between the amygdala and hypothalamus prevents mice from finding social interactions as rewarding as they would otherwise.

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March 2021
A digital rendering of a green neuron on black
News

Brain activity jump-starts autism-linked genes in human neurons

by  /  5 March 2021

Some neurons activate autism-linked genes when they fire, according to a new study.

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January 2021
Boy sleeping in low light
News

Brain-wave patterns flag sleep differences in dup15q syndrome

by  /  13 January 2021

Children with dup15q syndrome may have telltale patterns of brain activity during sleep and get less non-REM sleep than neurotypical children do.

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September 2020
Liquid medicine being poured from bottle onto spoon.
News

Bumetanide may benefit only a subset of autistic children

by  /  3 September 2020

Contrary to previous results, the blood pressure drug did not uniformly improve autism traits in a new clinical trial.

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March 2020
Close-up of mouse face and whiskers.
News

Sensory sensitivity in autistic people may stem from subset of neurons

by  /  27 March 2020

Mice missing an autism gene called SHANK3 tend to be hypersensitive to touch, which may stem from underactivity of neurons that normally dampen sensory responses.

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October 2019
a human brain model made of springs is shaking on its spring base
News

The link between epilepsy and autism, explained

by  /  21 October 2019

Autism and epileptic seizures often go hand in hand. What explains the overlap, and what does it reveal about autism’s origins?

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linked hands in a pattern intertwined with DNA showing some broken parts, symbolizing mutations
News

Rett syndrome’s link to autism, explained

by  /  21 October 2019

Studies of Rett syndrome hint at genes, cells and brain circuits that may be involved in autism — and may pave the way to treatments for both conditions.

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