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Spectrum: Autism Research News

Tag: copy number variation

November 2017
Mice lacking KCTD13 have shorter and fewer neuronal branches (middle and right) compared with controls (left).

Mouse study questions autism gene’s link to head size

by  /  30 November 2017

Deleting KCTD13, a gene in the autism risk region 16p11.2, has little effect on brain or head size in mice — contradicting results from a 2012 zebrafish study.

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black mice exiting hole

Learning shows sex bias in mice with mutation tied to autism

by  /  23 November 2017

Male mice with a genetic variant tied to autism may have learning difficulties that females with the variant do not.

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Two mice sniffing one another.

Drug boosts social behavior in mice with deletion tied to autism

by  /  1 November 2017

A drug that has shown promise for treating fragile X syndrome may ease features of another condition associated with autism.

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October 2017
Week of OctoberOct
16th
2017

Boy bias; incontinence issues; smart search and more

by  /  20 October 2017

A mouse model of autism reveals sex differences in brain function and behavior, incontinence and autism often co-occur, and a new literature search engine summarizes neuroscience hits into interactive visuals.

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Mother and daughter practicing writing.

Rare autism mutations linked to low intelligence

by  /  20 October 2017

People with autism who have rare, damaging mutations tend to have low scores on intelligence tests.

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Week of OctoberOct
2nd
2017

Cannabis candidate; omega add-on; oxytocin control and more

by  /  6 October 2017

A cannabis gel may ease features of fragile X syndrome, omega fatty acids show promise for autism in two trials, and oxytocin reinforces social behaviors through the brain’s reward pathway.

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Two children sitting at a garage sale table.

Scan of whole genomes ties regulatory regions to autism risk

by  /  4 October 2017

Children with autism may have an excess of spontaneous mutations in DNA that controls the expression of autism genes.

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August 2017
A family holding hands and walking down the sidewalk.

Whole genomes may power search for autism risk factors

by  /  23 August 2017

Scientists this week announced the release of nearly 7,000 whole-genome sequences from a collection of families that each have one child with autism.

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Week of AugustAug
7th
2017

Off-key outcomes; visualizing variants; urine indifference and more

by  /  11 August 2017

Music therapy proves ineffective for autism, brain structures differ with 16p11.2 duplications and deletions, and mice missing NLGN3 may influence the sociability of their littermates.

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Parents sitting in the dark watching TV and nursing a baby.

Genetic risk factors for autism may affect family size

by  /  10 August 2017

People who carry risk factors for autism but do not have the condition tend to have slightly fewer children than average, and have them later in life.

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