Researchers are studying how a combination of genetic ‘hits’ may contribute to autism’s diversity.
Certain repeated stretches of DNA that are linked to the expansion of the primate brain may also enhance autism traits.
Finding a mutation linked to autism traits can have life-changing consequences for autistic individuals and their families.
Autism may be just as common among children missing a segment of chromosome 16 as it is in those with an extra copy.
An analysis of spontaneous mutations in nearly 11,000 individuals with developmental delay or autism implicates 49 new genes.
A cellular pathway that helps neurons grow and move during fetal development may drive the changes in head size in some autistic people.
Clusters of brain cells — so-called ‘mini-brains’ grown in the lab — may help researchers understand how large stretches of duplicated or deleted DNA affect the brain.
Genes linked to autism in sequencing studies tend be located in long stretches of DNA that are duplicated or missing in some people with developmental conditions.