Spectrum: Autism Research News
Dup15q Alliance Scientific Meeting 2012
About 1 in 500 children referred to genetic testing for undefined developmental delay, intellectual disability, or autism have duplications of the 15q11-13 chromosomal region, according to a new analysis. That makes the region the second most common large genetic alteration linked to autism.
Researchers plan to develop pig models of Prader-Willi syndrome, an inherited disorder caused by the deletion of an autism-linked region of chromosome 15.
Researchers are beginning to tease apart how dosage of genes within the 15q11-13 chromosomal region contributes to autism symptoms.