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• Single-point mutations in the gene CYFIP1 can disrupt actin during brain development and lead to intellectual disability and autism. Spectrum has previously reported on cytoskeletal influences on neuronal function. Biological Psychiatry
• A reference trajectory of the functional connectome draws on brain-imaging data from tens of thousands of people up to age 80, according to a preprint. bioRxiv
• The International Society for Stem Cell Research has published recommendations for laboratory standards to improve the reproducibility of results. Stem Cell Reports
• Far-sightedness and pain insensitivity are traits of Lamb-Shaffer syndrome, which is caused by SOX5 gene variants and linked to autism and intellectual disability, according to an analysis of 20 people. Clinical Genetics
• Mental-health counseling appears to be the most valuable of services for autistic adults, according to self-report and actual use. Autism
• Microglia interact with neuronal synapses in several ways to affect connectivity and brain function. Science
  

  Repeat reactions: Autistic children (top row) habituate much more gradually to loud noises than do non-autistic children (bottom row).

• Postsynaptic densities mature two to three times more slowly in people than in monkeys or mice, according to a proteomic study across development. Nature
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• Rates of autism, attention-deficit/hyperactivity disorder, intellectual disability and other conditions are higher in children with congenital heart disease than in the general population. Circulation
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• An international consortium of experts has developed guidance on the diagnosis and treatment of neuropsychiatric conditions associated with tuberous sclerosis complex. Journal of Neurodevelopmental Disorders

Cite this article: https://doi.org/10.53053/CAVF4858