Ambitious venture aims to create a mouse for every gene
A multi-site collaborative venture between the U.S., Canada and Europe has created nearly 17,000 mouse embryonic stem cell lines, each lacking one of the genes in the mouse genome.
Efforts to ease the symptoms of autism are beginning to ramp up, with promising candidates in various stages of testing.
A multi-site collaborative venture between the U.S., Canada and Europe has created nearly 17,000 mouse embryonic stem cell lines, each lacking one of the genes in the mouse genome.
A powerful magnet that alters brain activity has shown that a brain region responsible for language may function differently in adults with Asperger syndrome than in controls, according to a study published in the July issue of the European Journal of Neuroscience.
Studying the infant siblings of children who have autism to identify early signs of the disorder is expected to have enormous impact on the field from a clinical and a basic science standpoint, says psychologist Karen Dobkins.
Human skin cells can be converted directly into functional neurons, bypassing a reprogramming step that is part of the typical procedure, according to a study published 26 May in Nature.
Sequencing an individual’s entire genome may be the key to tailoring treatments for heterogeneous disorders, suggests a study published 15 June in Science Translational Medicine.
The ever-curious and energetic Ricardo Dolmetsch is taking skin cells from individuals with various types of autism and turning them into neurons in the lab. The approach could reveal the cellular basis of the disorder and point to new treatments.
Several targeted trials on drugs that treat fragile X syndrome are under way. But accurate endpoints to measure the drugs’ effectiveness are crucial, argues developmental and behavioral pediatrician Randi Hagerman.
A new study calls into question the assumption that Rett syndrome is exclusively a neurodevelopmental disorder caused by the lack of a critical protein in utero.
A new opinion piece argues that the risks of early screening for autism outweigh the benefits. But the article does a poor job of articulating what these risks might be, instead focusing only on the fact that there are few good options available to children after their diagnosis.