A drug in trials for treating autism-related disorders can reverse memory problems and anxiety in adult mice lacking the schizophrenia gene DISC1 in some cells. The unpublished results were presented yesterday in Washington, D.C.
Spectrum: Autism Research News
Efforts to ease the symptoms of autism are beginning to ramp up, with promising candidates in various stages of testing.
Over the past 30 years, autism research pioneer Fred Volkmar says he has learned that researchers should be humble when assigning meaning to autism behavior, and seek to translate their findings into useful applications.
Adults with autism are more likely than controls to have certain chronic health conditions, such as high cholesterol, but are less likely to treat these with prescription drugs.
Postmortem brains from adults with autism have lower-than-normal levels of the fragile X mental retardation protein, which is missing in individuals with fragile X syndrome.
Stem cells reprogrammed to become neurons can provide a picture of gene expression in neurons that is traditionally available only from brain tissue.
Mice lacking a copy of SHANK3, a gene associated with autism and intellectual disability, show marked improvements in brain signaling after being treated with insulin-like growth factor 1, according to unpublished findings presented Saturday at the International Congress of Human Genetics in Montreal, Canada.
Mouse pups with a duplication of GTF2I, a gene linked to Williams syndrome and autism, show extreme separation anxiety when separated from their mothers, according to unpublished findings presented Thursday at the International Congress of Human Genetics in Montreal, Canada.
Pregnant women who take beta-2 adrenergic agonists, commonly prescribed to treat asthma, are no more likely to have a child with autism than are those who don’t take the drugs.
Children with autism who suffer from severe gastrointestinal problems show markedly lower-than-normal levels of enzymes needed to digest complex sugars, and of transporters that allow simple sugars to be absorbed into the blood.