New standards for animal studies, including an emphasis on replicating results and the publication of negative findings, are vital for research progress, says Jacqueline Crawley.
Spectrum: Autism Research News
Efforts to ease the symptoms of autism are beginning to ramp up, with promising candidates in various stages of testing.
Prenatal exposure to antibodies collected from the mothers of children with autism boosts stem cell proliferation in the brains of mice, according to two studies presented at the 2012 Society for Neuroscience annual meeting in New Orleans.
Neural stem cells derived from people with Rett syndrome show early signs of dysfunction, according to unpublished research presented at the 2012 Society for Neuroscience annual meeting.
Mice missing the autism-linked gene CNTNAP2 have broad defects in their oxytocin system, according to research presented Tuesday at the Society for Neuroscience annual meeting in New Orleans. Treatment with oxytocin alleviates social deficits in these mice.
Mouse studies of a promising treatment for Rett syndrome, already in clinical trials, offer a note of caution about the drug’s potential. Preliminary findings from the research, presented Sunday at the Society for Neuroscience annual meeting in New Orleans, show why mouse work remains important even after clinical trials are underway.