TOPIC

The Brain

Charting the structure and function of the brain’s many circuits may unravel autism’s mysteries.

November 2018
News

‘Mini-brains’ show realistic neuronal firing rhythms

by  /  4 November 2018

Brain organoids made from typical human stem cells begin to show synchronized neuronal firing patterns after growing in a dish for at least four months.

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A 3D rendering shows a neuron firing on black.
News

Tweak cleans up ‘pollution’ in images of firing neurons

by  /  3 November 2018

Targeting a fluorescent protein to the cell bodies of neurons enables researchers to clearly see which neurons fire when.

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News

Fever in pregnant rats alters pups’ social skills

by  /  3 November 2018

Fever in pregnant rats around the time of delivery disrupts their pups’ communication and social behavior.

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News

Decoy protein defangs immune molecule linked to autism

by  /  3 November 2018

A specially made ‘decoy’ protein prevents an immune molecule from crossing the placenta; the strategy may prevent the brain changes that lead to autism.

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San Diego, California, Cabrillo freeway, plane flying overhead.
News

Reactions from SfN 2018

by  /  1 November 2018

Spectrum heads to San Diego to cover the annual Society for Neuroscience conference.

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October 2018
News

Study calls into question chemical messenger’s role in autism

by  /  29 October 2018

New results from brain scans of adults with autism are at odds with the popular theory that the condition involves weak brakes on brain activity.

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Recordings from the mouse visual cortex flash pink and orange.
News / Toolbox

New tool provides real-time glimpse of brain activity in mice

by  /  26 October 2018

A transparent set of electrodes enables researchers to simultaneously record electrical signals and visualize neurons in the brains of awake mice.

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News

Misfiring visual cells may underlie key sensory problem in fragile X

by  /  17 October 2018

The motion perception difficulties seen in people with fragile X syndrome, a leading cause of autism, may stem from a faulty visual circuit.

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Illustration of human brain in brackets suggesting circuit alterations that is associated with certain genetic mutations.
Opinion / Viewpoint

Brain scans of sleeping mice hint at subtypes of autism

by  /  9 October 2018

Mapping the effects of autism mutations on mouse brain circuits may reveal subtypes of the condition in people.

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Neurons in lab grown brain glow green, red and blue.
News / Toolbox

New techniques extend tool kit for constructing ‘mini-brains’

by  /  5 October 2018

Two new methods for building ‘mini-brains’ may help researchers study how early brain development differs in people with autism.

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