The brains of mice carrying different mutations in the autism-linked gene TBR1 display different molecular changes yet similar structural changes, resembling those previously found in autistic people with TBR1 mutations.
Spectrum: Autism Research News
Charting the structure and function of the brain’s many circuits may unravel autism’s mysteries.
Sleep disruption early in life has long-lasting consequences for mice missing a copy of the autism-linked gene SHANK3.
Many brain regions develop differently between people with 22q11.2 duplications and deletions, and those trajectories also vary with a person’s diagnosis.
What these genes do and how they affect autism depends on when in development they’re studied, despite what classic ‘gene ontology’ analyses say.
A delayed brain response to viewing faces may predict lags in social-skill development in autistic people.
The method could boost reproducibility across brain imaging studies of autism.
People’s brains have a larger network of inhibitory interneurons than mouse brains do, according to a new study. Changes to that network could contribute to autism or other conditions, says lead investigator Moritz Helmstaedter.
Regions of the brain’s fear center expand in autistic children and teenagers with anxiety, but not in their autistic or non-autistic peers without anxiety.
A theoretical neuroscientist, Kennedy uses a blend of computational modeling and real-world experiments to understand how brain activity shapes the behaviors of animals that model autism and other conditions.