Developmental delay, intellectual disability and behavioral issues are common among people who have mutations in MYT1L, a gene with strong ties to autism.
Spectrum: Autism Research News
Charting the structure and function of the brain’s many circuits may unravel autism’s mysteries.
New software can automatically identify and quantify mouse social behavior from videos, saving researchers time.
Mice missing a copy of the gene SENP1 have atypical social behavior likely due to a signaling imbalance in the retrosplenial cortex.
Many genes linked to autism are switched on in the brain’s glia, cells that help neurons develop and synapses form.
Deleting a copy of the gene TBX1 depletes the fatty myelin insulation that surrounds neurons and reduces cognitive speed in mice.
Almost 60 percent of autistic people may have an average or above-average intelligence quotient, according to a new longitudinal study.
Clues that problems with mitochondria contribute to autism have been accumulating for decades. In the past five years, a mutant mouse and a flurry of findings have energized the field.
Model mice of the subtype also show hyperactivity in a signaling pathway called mTOR, bolstering the idea that distinct forms of autism have different biological roots and may require different treatment approaches.