Decoding sensory brain networks: A quick take at SfN with Ethan Scott
Scott describes his work on sound processing differences in the brains of zebrafish that model fragile X syndrome.
Charting the structure and function of the brain’s many circuits may unravel autism’s mysteries.
Scott describes his work on sound processing differences in the brains of zebrafish that model fragile X syndrome.
People with dup15q syndrome and those with idiopathic autism have similar patterns of altered gene expression in early brain development and later in life.
Rhythmic variations in the genes’ brain expression levels may help explain the sleep problems that often accompany the condition.
A new atlas reveals how the structural shake-ups within a cell’s genome differ by cell type and brain region over time.
Findings on microglia and other brain cell types bolster the animal’s validity as a model system for the condition.
Data from two separate research teams suggest the cells are key to sensory hypersensitivity in fragile X syndrome.
An analysis of 11 cortical regions shows anterior-to-posterior shifts in gene expression linked to autism.
The gene, YTHDF2, has not previously been linked to autism.
The developmental models have advantages over natural embryos and other synthetic models, such as organoids, but present technical and ethical challenges.
Collecting brain scans from thousands of people can be challenging in autism research; data-sharing and collaborative efforts can help drive results that stand up to statistical scrutiny.