TOPIC

The Brain

Charting the structure and function of the brain’s many circuits may unravel autism’s mysteries.

December 2018
Siblings, a baby and a toddler, play together at home.
Features / Deep Dive

How pregnancy may shape a child’s autism

by  /  5 December 2018

Autism is predominantly genetic in origin, but a growing list of prenatal exposures for mother and baby may sway the odds.

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Still from video shows a mouse embryo in development.
News / Toolbox

Microscope tracks cells in maturing mouse embryos

by  /  5 December 2018

A new microscope creates images of a mouse embryo as it grows from a ball of about 100 cells into a structure with a primitive heart and brain.

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November 2018
Black and white images shows human neurons grafted onto a mouse brain grow over time.
News / Toolbox

Human neurons take root in living mouse brains

by  /  30 November 2018

Neurons grown from human stem cells and grafted onto the brains of live mice mature and form connections like those in the fetal human brain.

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Three columns of brain images show patterns of brain connections.
News

Repetitive behaviors tied to brain activity patterns in toddlers

by  /  29 November 2018

Children who have repetitive behaviors, a core autism trait, may show particular patterns of brain activity as early as 1 year of age.

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News

Young children with autism may show brain-fluid buildup

by  /  19 November 2018

Autistic children aged 2 to 4 have about 15 percent more fluid between their skull and their brain than their typical peers do.

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News / Toolbox

Mouse brain atlas reveals details of developing cerebellum

by  /  16 November 2018

A new database displays gene-expression patterns in individual cells of the developing mouse cerebellum over time.

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News

Top autism gene may rewire brain by altering expression of other genes

by  /  15 November 2018

The autism gene TBR1 controls the expression of several other candidate genes that govern the architecture of the brain’s outer section.

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Purkinje neurons glow red in this section.
News

Cerebellum’s role in autism may depend on timing

by  /  12 November 2018

Two studies published in the past two months provide new clues to when and how the cerebellum contributes to autism.

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News

Neuron tag may shield synapses from brain’s pruning shears

by  /  12 November 2018

A protective molecular tag on neurons can prevent microglia, the brain’s immune cells, from trimming away their connections with other neurons.

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Delicate network of neurons and synapses.
News

Webbing around neurons altered in autism mouse models

by  /  8 November 2018

Lattice-like structures that surround neurons may be overly abundant — or scarce — in brain regions of three autism mouse models.

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