TOPIC

The Brain

Charting the structure and function of the brain’s many circuits may unravel autism’s mysteries.

April 2018
Opinion / Viewpoint

How to break new ground in the search for autism biomarkers

by  /  3 April 2018

A large dataset that catalogs the features of many brain conditions could transform the quest for biomarkers of autism.

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A microglia cell (red), touches the signal-receiving ends of neurons (green) in the brain
News

Microglia may have only small appetite for synapses

by  /  2 April 2018

Microglia come into frequent contact with synapses, the connections between neurons, but they appear to nibble on them rather than engulf and digest them.

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March 2018
Tiny particles (blue), along with light-sensitive proteins (green) and light, excite neurons (red) in a reward region of the mouse brain.
News / Toolbox

Tiny particles safely stimulate neurons buried in brain

by  /  30 March 2018

A new technology that converts near-infrared light to visible light can manipulate neurons nestled deep in the brain.

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closeup of a mouse eye
News

Gene on chromosome 16 may be valuable player in autism

by  /  29 March 2018

Deleting one copy of a gene called MVP impairs the brain's ability to adapt to changes in the environment.

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child writing on a piece of paper with intense focus.
News

Attention deficit disorder, autism share cognitive problems

by  /  22 March 2018

Children with autism may have many of the cognitive difficulties seen in children with attention deficit hyperactivity disorder.

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Multimedia / Webinars

Roundtable: Debating diagnostic criteria for autism

17 April 2018

Watch the complete replay of our roundtable on the utility of the DSM-5’s diagnostic criteria for autism. 

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illustration of mouse on sale in a city
News

‘Outmoded’ mouse models of autism may still yield new advances

by  /  21 March 2018

Many researchers question the value of three early mouse models of autism, but the models have their staunch supporters.

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Neurons from mice missing OTUD7A (right) have fewer spines than do those from controls (left).
News

Studies pinpoint key gene in region linked to autism

by  /  21 March 2018

A single gene, OTUD7A, may account for most of the features seen in people missing a segment of chromosome 15 known as 15q13.3.

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Diagram showing data motion of mice.
News

‘Syntax’ of mouse behavior may speak volumes about autism

by  /  21 March 2018

An algorithm that decodes and quantifies mouse body language could reveal the brain circuits underlying certain autism features.

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honeycomb shape with arrows shows the pattern of activity of rats in the maze
News / Toolbox

‘Honeycomb’ maze elevates testing of rodents’ spatial skills

by  /  16 March 2018

A maze comprising 37 hexagonal platforms may offer researchers an accurate measure of rodents’ ability to navigate their surroundings.

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