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Spectrum: Autism Research News

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The Brain

Charting the structure and function of the brain’s many circuits may unravel autism’s mysteries.

July 2011

Magnet reveals differences in Asperger syndrome brains

by  /  6 July 2011

A powerful magnet that alters brain activity has shown that a brain region responsible for language may function differently in adults with Asperger syndrome than in controls, according to a study published in the July issue of the European Journal of Neuroscience.

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Clinical research: Infertile women should be tested for fragile X

by  /  6 July 2011

Women with a mild version of primary ovarian insufficiency, a disorder that mimics the symptoms of menopause, should be tested for a mutation that can lead to fragile X syndrome, according to a study published 15 June in Human Reproduction.

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Studying infant sibs of children with autism spectrum disorder

by  /  5 July 2011

Studying the infant siblings of children who have autism to identify early signs of the disorder is expected to have enormous impact on the field from a clinical and a basic science standpoint, says psychologist Karen Dobkins.

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Genetics: Autism samples show altered gene expression in blood

by  /  5 July 2011

Blood cells from individuals who have autism produce less-than-normal amounts of SHANK3 and NLGN3 proteins, according to a study published 26 May in Molecular Autism.

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Cognition and behavior: Brain overgrowth in autism ends early

by  /  1 July 2011

The rapid brain growth seen in children with autism occurs early in life, before children reach 2 years of age, according to a study published in the May issue of Archives of General Psychiatry.

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June 2011

Imperfect mouse may illuminate autism syndrome

by  /  30 June 2011

A new mouse model of 15q duplication syndrome, a genetic disorder associated with autism, falls short of recapitulating the symptoms of the syndrome. But it nonetheless points to a cluster of well-known risk genes as the most likely culprits.

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Researchers make neurons directly from skin cells

by  /  29 June 2011

Human skin cells can be converted directly into functional neurons, bypassing a reprogramming step that is part of the typical procedure, according to a study published 26 May in Nature.

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Genetic roadmap

by  /  28 June 2011

Sequencing an individual’s entire genome may be the key to tailoring treatments for heterogeneous disorders, suggests a study published 15 June in Science Translational Medicine.

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Molecular mechanisms: Some synaptic proteins travel in groups

by  /  28 June 2011

Soluble proteins band together into temporary complexes to travel to the tips of neurons, according to a study published 12 May in Neuron. The study provides the first evidence-based model for slow, directed neuronal transport, answering a long-standing question in the field.

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Diagnostic tests for autism may miss many girls

by  /  27 June 2011

The symptoms of Asperger syndrome look slightly different in girls than in boys, according to a new study. However, gender differences in autism are poorly understood, and the results are preliminary, say other researchers.

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