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Spectrum: Autism Research News

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The Brain

Charting the structure and function of the brain’s many circuits may unravel autism’s mysteries.

September 2011

Genetics: Protein that regulates serotonin linked to autism

by  /  27 September 2011

A protein that regulates the development of serotonin-producing neurons in the brain is associated with autism.

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Brain activity triggers widespread epigenetic changes

by  /  26 September 2011

Methylation marks were thought to be permanent features of the genome, but a new study challenges that idea.

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Clinical research: Men may not outgrow autism-like behaviors

by  /  23 September 2011

Boys who have autism-like social deficits at 2 years of age retain about the same level of social impairment when they reach age 20.

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Social cues from bodies in motion lost to those with autism

by  /  22 September 2011

Two new studies suggest that people with autism don’t all have trouble detecting the motion of people and animals. What they do struggle with is picking up social information from bodies in motion.

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Molecular mechanisms: Fragile X brains have altered synapses

by  /  21 September 2011

Neurons in a mouse model of fragile X syndrome make more connections during a critical period in development compared with controls, but are slower to respond to signals.

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Cognition and behavior: Probiotics alleviate anxiety in mice

by  /  20 September 2011

Probiotic bacteria alleviate stress in healthy mice and modify the expression of receptors for a chemical messenger that inhibits signaling in the brain.

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Researchers map gene expression in layers of mouse brain

by  /  16 September 2011

A new atlas of gene expression patterns in the adult mouse brain shows how thousands of genes are turned on in specific layers of the cortex.

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Autism exome study pinpoints mutations in brain genes

by  /  14 September 2011

Children with autism carry many more spontaneous point mutations in genes expressed in the brain compared with their unaffected siblings, according to unpublished findings presented Monday at the World Congress of Psychiatric Genetics in Washington, D.C.

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Clinical research: Oxytocin alleviates social anxiety

by  /  14 September 2011

Individuals with fragile X syndrome make slightly more eye contact in stressful social situations after taking oxytocin compared with placebo.

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Researchers identify gene regulating amygdala volume

by  /  13 September 2011

A variant of the FGF14 gene may decrease the volume of the amygdala, a brain structure needed to interpret emotions in facial expressions, according to results presented on Sunday at the World Congress of Psychiatric Genetics in Washington, D.C.

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