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Spectrum: Autism Research News

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The Brain

Charting the structure and function of the brain’s many circuits may unravel autism’s mysteries.

October 2011

Cognition and behavior: Mouse model has autism-like brain

by  /  28 October 2011

A well-studied mouse model of autism has a smaller-than-normal volume in several autism-associated brain regions.

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Narrower amygdala scans lead to cleaner results

by  /  26 October 2011

Researchers have defined anatomical boundaries that minimize errors in brain-imaging measures of the amygdala, a region involved in emotion processing.

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Peer pressure

by  /  25 October 2011

Individuals with autism are no more likely to donate money when being observed than when alone.

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Artist's rendering of blue neurons in a network, with some connections firing, in yellow.

Molecular mechanisms: Autism gene tied to neuronal wiring

by  /  21 October 2011

An autism-linked protein helps wire neurons together, according to two studies published in late September.

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Stem cells pinpoint players in nerve cell development

by  /  19 October 2011

Stem cells reprogrammed to become neurons can provide a picture of gene expression in neurons that is traditionally available only from brain tissue.

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Growth factor improves autism symptoms in mice

by  /  19 October 2011

Mice lacking a copy of SHANK3, a gene associated with autism and intellectual disability, show marked improvements in brain signaling after being treated with insulin-like growth factor 1, according to unpublished findings presented Saturday at the International Congress of Human Genetics in Montreal, Canada.

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Researchers debut mice with links to Williams syndrome

by  /  17 October 2011

Mouse pups with a duplication of GTF2I, a gene linked to Williams syndrome and autism, show extreme separation anxiety when separated from their mothers, according to unpublished findings presented Thursday at the International Congress of Human Genetics in Montreal, Canada.

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Fast-evolving gene is key player in brain development

by  /  14 October 2011

A gene that changed rapidly after the human genome diverged from that of Neanderthals plays a critical role in brain development, according to unpublished results presented Thursday at the International Congress of Human Genetics in Montreal, Canada.

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Molecular mechanisms: Pathway linked to regressive autism

by  /  12 October 2011

Defects in a signaling pathway that regulates learning and memory could underlie regressive autism, a sudden loss of language or social ability.

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Easy-to-make solution turns brains transparent

by  /  12 October 2011

Three common laboratory chemicals are all scientists need to create see-through brains ideal for visualizing complex neural circuits.

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