Gene in autism risk region plays key role in brain development
Mice missing TAOK2, a gene in a segment of chromosome 16 linked to autism, have big brains, immature neuronal junctions and asocial behavior.
Autism’s core symptoms accompany a constellation of subtle signs that scientists are just beginning to unmask.
Mice missing TAOK2, a gene in a segment of chromosome 16 linked to autism, have big brains, immature neuronal junctions and asocial behavior.
Deleting one copy of a gene called MVP impairs the brain's ability to adapt to changes in the environment.
Customized cutoff scores could boost the accuracy of a popular autism screen in certain populations.
Some individuals who have autism mutations show no signs of the condition; understanding why may lead to treatments.
Children with autism may have many of the cognitive difficulties seen in children with attention deficit hyperactivity disorder.
Many tests for unusual behavior in mice are prone to operator error. Here’s how to avoid common traps.
After more than a decade of effort, scientists are questioning whether mouse models of autism can ever capture the social deficits seen in people with the condition.
A mouse model based on exposure to an epilepsy drug offers a useful window into the brain circuits altered in autism.
Researchers have developed behavioral measures that can accurately diagnose autism in people; these lessons can and should be applied to mice.
An algorithm that decodes and quantifies mouse body language could reveal the brain circuits underlying certain autism features.