Rare, spontaneous mutations rife in schizophrenia cases
Rare, spontaneous mutations could account for at least ten percent of cases of schizophrenia, according a study published online last week.
Autism’s core symptoms accompany a constellation of subtle signs that scientists are just beginning to unmask.
Rare, spontaneous mutations could account for at least ten percent of cases of schizophrenia, according a study published online last week.
At first glance, the waiting room at the Ministry of Health Hospital in Muscat, Oman, may look different than that of your average American hospital. Men dressed all in white and women in black burqas wait in separate rooms, even if they are members of the same family. But talking to these families soon reveals just how similar they are to their American counterparts, says Christopher Walsh, a neurologist who has studied neurodevelopmental disorders in the Middle East for nearly 10 years.
In 1985, Simon Baron-Cohen, Alan Leslie and Uta Frith reported for the first time that children with autism systematically fail the false belief task.
Sitting on a sofa in his office at the Yale Child Study Center, Ami Klin plays a movie clip on a tiny laptop. The clip stars a younger Klin, with larger glasses but the same easy smile, vying for the attention of a young girl with autism. His face inches from hers, he speaks in a warm, animated voice. But the girl never looks from the toy blocks in her hands. Suddenly, she spots an orange M&M in the far corner of the room and scoots after it.
For parents of children with autism, bedtime can be a boondoggle.
In the past two weeks, autism researchers and advocacy groups have been agog with news that autism could be linked to an extremely rare group of metabolic diseases.
Autism is caused by poor parenting, particularly by ‘frigid’ mothers who reject their children. Such a statement would seem bizarre today. But 30 years ago parents, especially mothers, were blamed for their childrenʼs autism. But then in 1977, one study, published in the Journal of Child Psychology and Psychiatry, single-handedly turned the field around to recognize the importance of genetics.
Serotonin is most commonly talked about in association with depression and anxiety. But for nearly 50 years, hyperserotonemia ― an elevated level of blood serotonin ― has been noted in roughly a third of autism cases.
For children with autism who have trouble interacting with their peers, virtual characters may be a way to improve language skills ― and perhaps more.
Are older fathers more likely to have children with autism? A series of epidemiological studies is giving credence to the idea, suggesting that, with age, sperm may accumulate damage that increases risk in the next generation.