Multiple diagnoses
A whopping 95 percent of children with autism have at least three other psychiatric disorders, and 74 percent have five or more, according to a study in the Journal of Autism and Developmental Disorders.
Autism’s core symptoms accompany a constellation of subtle signs that scientists are just beginning to unmask.
A whopping 95 percent of children with autism have at least three other psychiatric disorders, and 74 percent have five or more, according to a study in the Journal of Autism and Developmental Disorders.
Researchers are tinkering with mouse models to investigate the function of a protein that helps wire neurons together and that has repeatedly been linked to autism. Three such reports of the protein, neuroligin-1, have appeared this year.
Two independent teams have identified the genetic culprits of three rare, inherited diseases by sequencing the genomes of several members of the same family. As the cost of whole-genome sequencing plummets, this family-based approach will reveal candidate genes not just for rare diseases but for common, complex disorders such as autism, experts say.
Scientists have been unable to replicate work showing an association between oxytocin receptor genes and autism.
Despite dozens of studies, researchers have not been able to agree on whether people with autism have trouble with planning skills. The inconsistency in results may be because of differences in short-term memory, according to a new study.
Two independent teams have discovered key molecular steps in the way a single gene disrupts the connections between neurons in individuals with Angelman syndrome. Because the gene, UBE3A, has also been linked to autism, the findings could help scientists understand and treat a range of neurodevelopmental disorders.
Attention deficit hyperactivity disorder (ADHD) and autism may have more in common than childhood onset and a few similar symptoms. New research suggests the conditions share genetic roots.
Many parents of children with autism show some mild traits of the disorder. Research on this group — labeled with the ‘broad autism phenotype’, or BAP — suggests that the genetic underpinnings that lead to language or social problems can manifest in very different ways.
Several studies in the past year in people, mice and honeybees have tied autism to a protein that helps neurons communicate. Problems with the protein, neurexin 1, are associated with a wide range of autistic behaviors, such as impaired social interactions, anxiety and problems with learning and memory.
Toddlers with autism pay less attention to faces than do healthy controls, but both groups give equal attention to objects, according to a study published in the Archives of General Psychiatry. The findings challenge the idea that individuals with autism have a generalized problem with attention, suggesting instead that they struggle with attending specifically to social stimuli, researchers say.