Power shortage
One of the largest genome-wide association studies for autism spectrum disorders, reported last week in Human Molecular Genetics, allows only one definitive conclusion: it isn’t large enough.
From funding decisions to scientific fraud, a wide range of societal factors shape autism research.
One of the largest genome-wide association studies for autism spectrum disorders, reported last week in Human Molecular Genetics, allows only one definitive conclusion: it isn’t large enough.
Toddlers who abruptly lose language, social or other developmental skills are more likely to have severe autism a few years later compared with children who have consistent delays from an early age. That’s the conclusion of the largest study thus far of autism onset patterns, published in the Journal of Autism and Developmental Disorders.
Children with autism are known to have strange rhythms and pitch to their speech, and they speak less often or for shorter periods. Based on these patterns, a company promises to accurately identify children with the disorder.
Scientists have for the first time captured a dynamic picture of brain defects in young mouse models of fragile X syndrome. The findings appeared in June in the Journal of Neuroscience.
The mouse brain has more than 1,300 regions for which the copy from one parent is expressed more often than the one from the other parent, according to two studies published today in Science. These so-called imprinted genes have been proposed to cause some cases of autism, but the researchers say their findings do not support that theory.
A clever new method records brain activity during live, back-and-forth social interactions and could help scientists study joint attention — the act of looking at an object the same time someone else does.
The U.S. government last week announced a $1 million multi-agency initiative that will evaluate how many new ideas, jobs and medical advances have been generated by its investment into scientific research.
The challenge of finding jobs for adults with autism is the focus of a special issue of the Journal of Vocational Rehabilitation. With the right training and tools, the articles suggest, it’s possible for many people with the disorder to be gainfully employed.
Chromosomal microarray analysis, which screens the entire genome for tiny blips in the sequence, should be the first genetic test performed when diagnosing autism, says a consortium of clinical geneticists. The recommendation comes on the heels of a study that found the test is three times more effective at spotting autism variants than are standard clinical methods.
Some children with autism prefer to look at geometric patterns rather than at ‘social’ images of other children — and this tendency is obvious as early as 14 months of age, according to a poster presented today at IMFAR 2010 in Philadelphia.