Combining functional magnetic resonance imaging of rat brains with a technique that uses light to detect neuronal activity can help researchers hone in on the source of the activity, according to a study published 6 May in Nature Methods.
Spectrum: Autism Research News
Science & Society
From funding decisions to scientific fraud, a wide range of societal factors shape autism research.
Researchers have identified deletions in SHANK1 — the third member of a gene family that is closely linked to autism — in five men with the disorder, they reported 4 May in the American Journal of Human Genetics. This is the first study linking SHANK1 mutations to people with autism.
Researchers have created sponge-like assemblies of hundreds of thousands of short fragments of RNA, which can be used to dampen the expression of certain genes, according to a study published 26 February in Nature Materials.
Large-scale swapping of genetic material between chromosomes may play an important role in autism, according to a study published 27 April in Cell.
Postmortem brain tissue from people with autism shows differences in the expression of genes involved in a number of molecular pathways, including those that control cortical patterning, programmed cell death and differentiation, according to research published last month in PLoS Genetics.
A ten-year initiative announced last month by the Allen Institute for Brain Science aims to catalog the development, structure and function of neural circuits in the brain at an unprecedented level of detail.
A computerized video analysis tool can simultaneously track two mice and catalog their social interactions. The results were published 4 March Nature Methods.