Rett syndrome’s link to autism, explained
Studies of Rett syndrome hint at genes, cells and brain circuits that may be involved in autism — and may pave the way to treatments for both conditions.
Rare or common, inherited or spontaneous, mutations form the core of autism risk.
Studies of Rett syndrome hint at genes, cells and brain circuits that may be involved in autism — and may pave the way to treatments for both conditions.
Advances in research and help from families have brought scientists to the brink of an effective therapy for Angelman syndrome.
A new autism mouse model carries the same mutation in a gene called ADNP that is seen in autistic people.
Exposure to infection in utero may speed up the expression of many genes linked to autism — and hasten changes in brain anatomy.
Researchers have identified mutations within regulatory regions that are likely to contribute to autism, using a speedy system of DNA ‘barcodes.’
Deleting an autism gene called TRIO derails neurons’ journey to their destination.
Mouse models of two genetic conditions related to autism show abnormalities in their movement patterns.
Injecting the gene-editing tool CRISPR into the brains of mice may reverse the effects of an autism mutation at any age.
Injecting cells called interneurons into the brains of a mouse model of autism restores typical social behavior. But the reason for this effect is a puzzle.
Neurons derived from autistic people with enlarged brains show extensive damage to long genes.