Brothers and sisters of people with autism are both about two to three times more likely than the general population to have an autistic child themselves.
Spectrum: Autism Research News
Rare or common, inherited or spontaneous, mutations form the core of autism risk.
Correcting an autism gene mutation in fetal mice lessens some autism-like behaviors after birth.
A new study highlights the challenge of distinguishing genetic variants linked to autism from those associated with cognitive development.
The relative contributions of genetic and environmental factors to autism have held steady over multiple decades, according to a large twin study.
Many genes in a brain region implicated in autism change expression patterns in late fetal development, depending on differences in neighboring DNA.
Mice missing DLG2, a protein central to neuronal activity, are anxious, sleep poorly and overgroom themselves.
A comprehensive atlas of gene expression by brain region could spur new research on autism.
Individuals with mutations in an autism gene called TRIO may have a range of conditions, including intellectual disability and anomalous head size.
Mice missing an autism gene called SHANK3 tend to be hypersensitive to touch, which may stem from underactivity of neurons that normally dampen sensory responses.